netFormulary
 Report : A-Z of formulary items 05/12/2020 22:55:45
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Section Name Details
10.01.03 Abatacept Orencia® Intravenous infusion 250mg vial
Injection 125mg pre-filled syringe
02.09 Abciximab  Injection - Restricted for stents only
08.03.04.02 Abiraterone Zytiga®
04.10.01 Acamprosate Campral EC® Tablet 333mg
  • Usual dose range: Bodyweight OVER 60Kg 666mg TDS, Bodyweight UNDER 60Kg 666mg breakfast, 333mg midday and 333mg at night
    		•
    06.01.02.03 Acarbose Glucobay® Tablet50mg 100mg
  • Useful in the occasional overweight patient but limited by gastrointestinal intolerance

    		•
    02.08.02 Acenocoumarol  Tablet
  • Only used for those patients intolerant of warfarin and phenindione, or existing patients
    		•
    20 Acetarsol Suppositories  
  • FORM AND STRENGTH: Suppository 250mg
  • INDICATION: Drug resistant proctitis
  • DOSE: 250mg twice daily
  • PACK SIZE:
  • SUPPLIER: Cardinal Health Martindale
  • LICENSE TYPE: UK unlicensed specials manufacturer

  • PRESCRIBING CONSULTANT: Dr C Kenneth
  • DATE AUTHORISED: 16/03/2012
    		•
    11.06 Acetazolamide Diamox® Tablets 250mg, Capsules MR 250mg
    11.08.02 Acetylcholine Chloride Miochol-E®
    03.07 Acetylcysteine 
    11.08.01 Acetylcysteine 
    18 Acetylcysteine Parvolex
    20 ACETYLCYSTEINE 10% PRESERVATIVE FREE 
  • FORM AND STRENGTH: 10% preservative free eye drops
  • INDICATION: Severe dry eyes
  • SUPPLIER: Moorfields Pharmaceuticals
  • PRESCRIBING CONSULTANT: Dr A Reynolds
  • DATE AUTHORISED: 26/07/2012
    		•
    11.08.01 Acetylcysteine 5% with Hypromellose 0.35% Ilube® Eye drops
    20 ACETYLCYSTEINE granules 
  • FORM AND STRENGTH: Granules 1g, capsules 600mg
  • INDICATION: Idiopathic Pulmonary Fibrosis
  • SUPPLIER: IDIS
  • PRESCRIBING CONSULTANT: Dr B Jacobs
  • DATE AUTHORISED: Granules 20/12/2005, Capsules 13/06/2007
    		•
    05.03.02.01 Aciclovir 
    13.10.03 Aciclovir 
    24.01 Aciclovir 

    Indication:

    Herpes zoster, treatment 
    Varicella zoster, treatment 

    Dose:

    20mg/kg every 8 hours 

    Administration:

    Dilute to concentration of 5 mg/mL with Sodium Chloride 0.9% or Glucose 5% and give over 1 hour;

    May be administered in a concentration of 25 mg/mL using a suitable infusion pump and central venous access and given over 1 hour.

    Monitoring:

    Renal function

    Further Info:

    Maintain adequate hydration

    Supply:

    Available on NNU as a stock item.

     Y&H ODN formulary

     
    11.03.03 Aciclovir eye ointment Zovirax® Eye ointment 3%
    13.05.02 Acitretin Neotigason® Capsule 10mg, 25mg
  • Dermatology specialist only

    		•
    20 Acitretin oral suspension 
  • FORM AND STRENGTH: 1mg/ml oral suspension
  • INDICATION: Harlequin Icthyosis
  • SUPPLIER: Novo labs 0116 2230099
  • PRESCRIBING CONSULTANT: Dr Heike Bauer (17/05/2007) and Dr Chris Day (20/01/2010)
    		•
    03.01.02 Aclidinium Eklira Genuair®
  • Inhalation powder inhaler (400 micrograms/dose)
    		•
    18 Activated charcoal 
    06.01.01.01 Actrapid® Soluble insulin
  • Short acting human soluble insulin
  • 10mL vial
    • 01.05.03 Adalimumab Amgevita

    Amgevita is the brand of choice at BTHFT, Humira can only be prescribed if approved by DTC.

    TA187: Infliximab and adalimumab for the treatment of Crohn's disease

    TA329: Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy

     
    10.01.03 Adalimumab Humira® Subcut injection 40mg prefilled syringe
  • Alternate week dosing increased to weekly if necessary
  • On recommendation from specialist consultant
    • 13.05.03 Adalimumab Amgevita

    TA146: Adalimumab for the treatment of adults with psoriasis

    TA187: Infliximab and adalimumab for the treatmetn of Crohn's disease 

    TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis

    TA195: Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor

    TA329: Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy

    TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis

    TA375: Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed

    TA392: Adalimumab for treating moderate to severe hidradenitis suppurativa

    TA455:Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people

    TA460: Adalimumab and dexamethasone for treating non-infectious uveitis

     
    13.05.03 Adalimumab Amgevita

    Amgevita is brand of choice at BTHFT. Humira should only be prescribed if approved to do so by DTC.

    To be prescribed as per NICE guidelines:

    TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis

    TA146: Adalimumab for the treatment of adults with psoriasis

    TA392: Adalimumab for treating moderate to severe hidradenitis suppurativa

    TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people

     
    13.06.01 Adapalene Epiduo® Contains adapalene 0.1% and benzoyl peroxide 2.5%
    Gel
    13.06.01 Adapalene Differin® Cream and Gel
    09.06.04 Adcal D3 Dissolve® 
    • Colecalciferol 400 units + calcium carbonate 1500mg per tablet
    • For patients who cannot chew or swallow tablets or for giving via an enteral tube
    09.06.04 Adcal D3® 
    • Colecalciferol 400 units (10 micrograms) + calcium carbonate 1500mg (calcium 600mg) per tablet
    09.06.04 Adcal D3® Caplets 
    • Colecalciferol 200 units (5 micrograms) + calcium carbonate 750mg (calcium 300mg) per caplet
    • For patients who cannot tolerate Adcal D3 chewable tablets but can swallow tablets
    05.03.03 Adefovir Dipivoxil Hepsera®
    02.03.02 Adenosine  Injection
    Secondary care only
    24.01 Adrenaline 

    Indication:


    Acute hypotension


    Dose:


    Consider starting at 100nanograms/kg/min.
    Higher doses up to 1.5 micrograms/kg/minute have been used in acute hypotension


    Administration


    Continuous IV infusion

    USE GUARDRAILS ON INFUSION PUMP

    3000 microgram in 50 ml 5% or 10% glucose. (60micrograms/ml)


    Monitoring


    BP, Heart rate, Peripheral perfusion, Blood sugars, Blood gas


    Further Info:

    CHECK STRENGTH OF AMPOULE!

    Compatibility: See medusa.

    Supply:
    Available from pharmacy as a stock item. DSU can make named patient syringes on request. Contact ward pharmacist  

    Y & H ODN formulary
    02.07.03 Adrenaline / Epinephrine  Injection

  • Adult dose is 10ml of 1:10,000 given IV (Note: For anaphylaxis the dose is 0.5ml of 1:1,000 given IM ).

    • 03.04.03 Adrenaline / Epinephrine  Injection
    Treatment of anaphylaxis
    03.04.03 Adrenaline / Epinephrine  
    03.04.03 Adrenaline / epinephrine EpiPen® Treatment of anaphylaxis
    08.01.05 Afatinib 
    08.01 Aflibercept Zaltrap®
    11.08.02 Aflibercept Eylea® Intravitreal injection
    04.03.04 Agomelatine  Tablets 25mg
  • Usual dose range 25-50mg daily
  • Max daily dose 50mg
  • Max single dose 50mg
    		•
    09.02.02.02 Albumin Solution 
    13.11.01 Alcohol 
    06.06.02 Alendronic Acid  Tablet 70mg
  • 70mg once WEEKLY dose
    		•
    06.06.02 Alendronic acid Binosto®
    • Restricted for use in patients with true swallowing difficulties (e.g. strictures) or those truly intolerant of bisphosphonate tablets despite the addition of a PPI.
    09.06.04 Alfacalcidol 
    15.01.04.03 Alfentanil 
    09.08.01 Alglucosidase Alfa Myozyme®
    02.12 Alirocumab Praluent®
  • For use in line with NICE TA393
    		•
    02.05.05.03 Aliskiren  Tablet

  • for specialist cardiology initation only
    		•
    13.05.01 Alitretinoin Toctino® Capsules
  • Dermatology specialist use only
  • Restricted to use in adult patients with severe chronic hand eczema unresponsive to treatment with potent topical corticosteroids in accordance with NICE TAG 177.

    		•
    10.01.04 Allopurinol Zyloric®
    10.01.04 Allopurinol 
    09.06.05 Alpha Tocopheryl Acetate 
    07.04.05 Alprostadil Caverject® Intracavernosal Injection
    07.04.05 Alprostadil MUSE® Urethral application
    24.01 Alprostadil Prostin VR

    Indication:
    Open/maintain patency of the ductus arteriosus
    Dose:
    12.5-100 nanograms/kg/min
    But higher doses may be used e.g. 200 nanograms/kg/min
    If well start at 12.5 or 25 nanograms/kg/min
    Unwell babies with ?duct dependent problem expect to need ventilation, start at 100nanograms/kg/min
    See regional guidance link

    Administration

    USE GUARDRAILS ON INFUSION PUMP
    300micrograms in 50ml in 5% glucose 
     
    Monitoring
    Watch for apnoea(especially in U&E, bloods sugars, reflux.
    Further Info:
    Undiluted solution must NOT come into contact with the barrel of the plastic syringe; add the required volume of alprostadil to a volume of infusion fluid in the syringe and then make up to final volume.
    Supply:

    Available on NNU as a stock item.

    Available from Pharmacy DSU

    Stored in Fridge
    02.10.02 Alteplase  Injection (secondary care only)

  • Actilyse®
  • Actilyse Cathflo®. For thrombolytic treatment of occluded venous access devices only
    		•
    11.99.99.99 Alteplase intravitreal injection  Intravitreal injection 25microgram in 0.1mL
    13.12 Aluminimum Chloride Hexahydrate 20% in Alcoholic Base Driclor®
    13.12 Aluminimum Salts 
    01.02 Alverine Citrate Spasmonal® Capsules, 60mg and 120mg (forte)
    04.09.01 Amantadine Hydrochloride Symmetrel®
    05.01.04 Amikacin 
    24.01 Amikacin 

    Indication:
    Gentamicin resistant gram negative bacilli
    Dose:
    15mg/kg
    36 hourly in babies 24 hourly for all other babies
    Administration
    Slow IV bolus over 3-5minutes or by infusion

    See Medusa
    100mg in 2 ml ampoule


    Monitoring
    The target trough is <8mg/L
    Further Info:
    Samples need to reach our lab by 2.30 – will then be sent to Leeds – goes to Bristol via an overnight service – levels available the following day – should appear on ICE around late morning. Mon- Fri service only – so levels will be available on a Saturday, but levels done after Fri afternoon will not be available till Tuesday morning.
    Supply:
    Available from pharmacy on a named patient basis.
    02.02.03 Amiloride Hydrochloride  Tablet 5mg, Oral solution 5mg/5ml
  • Tablets can be crushed and dispersed in water if necessary
    		•
    03.01.03 Aminophylline Phyllocontin Continus® Tablets M/R 225mg
  • 350mg tablets not stocked at BTHFT
    		•
    03.01.03 Aminophylline IV  Injection, 25mg/ml
    02.03.02 Amiodarone  Tablet, Injection (secondary care only)
  • Tablets can be crushed and mixed with water
    • 04.02.01 Amisulpride 
    04.03.01 Amitriptyline 
    02.06.02 Amlodipine  Tablet
  • If needed tablets can be crushed and dispersed in water.

    Restricted Item Amlodipine Oral Solution restricted for those patients with established swallowing difficulties or NG tube administration
    		•
    13.10.02 Amorolfine Loceryl®
    05.01.01.03 Amoxicillin 
    24.01 Amoxicillin 

    Indication:
    Infection - broad spectrum
    Dose:
    50 mg/kg/dose every 12 hours <7days
    50 mg/kg/dose every 8 hours 7-21 days
    50 mg/kg/dose every 6 hours >21 days
    Administration
    See BNFc 

    IV doses less than 30mg/kg can be given by IV slow bolus

    IV doses over 30mg/kg can be given by IV infusion over 30minutes

    Monitoring
    Renl function
    Further Info:
    Active againist: listeria, haemophyllus, enterococci, streptococci, pneumococci, salmonella,shigella and many coliforms
    Supply:

    Available on NNU as a stock item.
    05.02 Amphotericin AmBisome®
    24.01 Amphotericin (liposomal) Ambisome

    Indication:
    Systemic fungal infections
    Dose:
    2 mg/kg/day.
    Doses up to 5mg/kg/day have been used in neonates.
    Administration
    IV infusion over at least 30 minutes.
    Amphotericin MUST be diluted in Glucose 5% for infusion.
    Final concentration in neonates must be 1mg/ml
    Lines MUST be flushed with Glucose 5% ONLY.
    A test dose of 100micrograms over 10 minutes may be considered in older babies to reduce risk of anaphaylaxis.
    Monitoring
    Renal function
    Potassium
    Further Info:
    Active against aspergillosis, candidasis, coccidoidomycosis and cryptococcosis.
    Supply:
    See Neonatal formualary for further information OOH. Vials are available from pharmacy as a named patient supply OOH.
    08.01.05 Amsacrine Amsidine®
    09.01.04 Anagrelide  Capsule
  • On Haematologist advice only.
    		•
    10.01.03 Anakinra Kineret® Prefilled syringe 100mg (subcut)
  • Daily dose
    		•
    08.03.04.01 Anastrozole 
    12.03.01 Antacid with Oxetacaine  Each 5ml contains 10mg Oxetacaine, Aluminium hydroxide equivalent to 200mg aluminium oxide + 100mg magnesium hydroxide

  • Indicated for painful swallowing, during and following radiotherapy to the head & neck and chest areas. Should be reserved for patients with oral mucositis and oesophageal lesions which are causing painful swallowing. Consider the use of a simple antacid first line.
    		•
    11.04.02 Antazoline 0.5% with Xylometazoline 0.05% Otrivine-Antistin®
    14.05.03 Anti-D (Rh0) Immunoglobulin Rhophylac®
    08.02.02 Anti-human thymocyte immunoglobulin (rabbit)  Thymoglobuline®
    01.07.01 Anusol®   Ointment, Cream, Suppositories
    02.08.02 Apixaban  Tablets 2.5mg amd 5mg

    POSITION STATEMENT TO ADD
    04.09.01 Apomorphine 
    11.08.02 Apraclonidine Iopidine®
    08.02 Apremilast  Otezla®
  • For use in line with NICE TA419
    		•
    13.05.03 Apremilast Otezla

    Oral tablets

    As per NICE guidelines: 

    TA419:Apremilast for treating moderate to severe plaque psoriasis

    TA433: Apremilast for treating active psoriatic arthritis 
    04.06 Aprepitant Emend® Capsules
  • For oncology patients only
    • 13.02.01 Aqueous Cream BP  Cream
  • Not recommended for use in children
  • Only use a soap substitute, not as a moisturiser
    		•
    04.02.01 Aripiprazole Abilify® Tablet
    Dispersible tablets
    Liquid
    Injection (IM use)
    Injection (prolonged release suspension for injection)
    08.01.05 Arsenic Trioxide Trisenox®
    15.02 Articaine Hydrochloride with Adrenaline Septanest®
    09.06.03 Ascorbic Acid  Tablets 50mg, 100mg, 200mg, 500mg
    04.07.01 Aspirin  Tablet dispersible and E/C, 75mg and 300mg, Suppository
    02.09 Aspirin (antiplatelet)  Tablets - dispersible and EC, (Suppository - Named patient use)
  • Enteric coated aspirin is second line to dispersible aspirin in line with UKMI Q&A below
  • For recommendation for use of aspirin in pregnant women at high risk of pre-eclampsia see NICE CG107.

    • 05.03.01 Atazanavir Reyataz® specialist consultant
    02.04 Atenolol  Tablet, Liquid, (Injection - secondary care only)
    04.04 Atomoxetine Strattera® Capsules 10mg and 40mg
  • Drug treatment of attention deficit hyeractivity disorder (ADHD)
  • Usual dose range 80mg-100mg
  • Max daily dose 120mg (unlicensed)
  • Max single dose 120mg (unlicensed)
    		•
    02.12 Atorvastatin  Tablets
  • If needed tablets can be crushed and dispersed in water
    		•
    07.01.03 Atosiban Tractocile® Injection 7.5mg/ml
    24.01 Atracurium 

    Indication:
    Short acting muscle relaxant
    Dose:
    A 500microgram/kg stat dose can produce muscle relaxation for up to 30 mins.
    A continuous infusion of 400micrograms/kg/hour will provide continual neuromuscular blockade in neonates.
    Administration

    USE GUARDRAIL INFUSION PUMP

    25mg in 25mls (1mg/ml).
    Infusions made up in 5% dextrose need to be made up every 8 hours, while those in saline can be changed every 24 hours (see datasheet, not neonatal formulary)


    Monitoring

    Further Info:
    In babies requiring paralysis consider sedation and pain relief were necessary.
    Supply:
    Available from pharmacy as a stock item

    Stored in fridge

    15.01.05 Atracurium Besilate 
    15.01.05 Atracurium Besilate Tracrium®
    15.01.03 Atropine 
    18 Atropine 
    11.05 Atropine Sulphate  Eye drops 0.5% and 1%, Minims 1%
    10.01.03 Auranofin Ridaura®
    07.04.05 Avanafil Stendra®
    13.02.01 Aveeno®  Cream, Bath oil
    08.01.03 Azacitidine Vidaza®
    01.05.03 Azathioprine  Tablets 25mg, 50mg, Suspension SF 50mg/5ml
    08.02.01 Azathioprine 
    10.01.03 Azathioprine 
    13.05.03 Azathioprine 

    Oral treatment

    SWYAPC shared care guidelines
    11.04.02 Azelastine Optilast® Eye drops 0.05%
    05.01.05 Azithromycin 
    11.03.01 Azithromycin Azyter® eye drops single use 1.5%
    24.01 Aztreonam  Indication:
    Infection- limited to Gram-negative aerobic bacteria Pseudomonas aeruginosa, Neisseria meningitidis, Neisseria gonorrhoeae and Haemophilus influenza.
    Dose:
    30 mg/kg/dose bd in preterm
    30 mg/kg/dose tds in term <7days
    30mg/kg/dose in term neonates >7days
    Reduce dose in renal impairment
    Administration
    Slow bolus over 3-5 mins or as infusion
    For intermittent intravenous infusion, dilute reconstituted solution further in Glucose 5% or Sodium chloride 0.9% to a concentration of less than 20 mg/mL; to be given over 20–60 minutes
    Monitoring
    Renal function
    LFT
    Further Info:
    Reduce dose in renal impairment
    Moderate renal failure give 50% of dose
    In Severe renal failure give 25% of dose
    Supply:
    Available from pharmacy on named patient request.
    05.01.02.03 Aztreonam nebuliser solution Cayston®
    10.02.02 Baclofen 
    12.02.03 Bactroban Nasal® Mupirocin 2% in White Soft Paraffin

    Nasal ointment

    • July 2014 - ongoing manufacturing problem - use naseptin as an alternative (check for peanut allergy)
    • MRSA suppression: Three times daily for 5 days
    01.05.01 Balsalazide Sodium Colazide® Capsules 750mg
    13.02.02 Barrier preparation Metanium®
    13.02.02 Barrier preparation Siopel® Cream
    13.02.02 Barrier preparation Sudocrem®
    08.02.04 BCG bladder instillation OncoTICE®
    14.04 BCG vaccine Intradermal 
    03.02 Beclometasone Clenil Modulite® Aerosol Inhaler
  • Available strengths 50mcg/dose, 100mcg/dose, 200mcg/dose and 250mcg/dose
    		•
    03.02 Beclometasone Qvar® Aerosol and Breath-actuated inhaler
  • Prescribe by brand
  • Aerosol 50mcg/dose, 100mcg/dose
  • Easi-breathe 50mcg/dose, 100mcg/dose
  • Autohaler not stocked within BTHFT

  • Qvar is not interchangeable with other CFC-free beclometasone inhalers, Qvar is approximately twice as potent as Clenil
    		•
    03.02 Beclometasone and formoterol Fostair® Aerosol Inhaler
  • Beclometasone 100 micrograms and formoterol 6 micrograms
    		•
    12.02.01 Beclometasone Dipropionate  Nasal spray 50micrograms per spray
    03.02 Beclometasone with formoterol and glycopyrronium Trimbow®
    • Trimbow 87/5/9 MDI
    08.01.01 Bendamustine 
    02.02.01 Bendroflumethiazide  Tablet 2.5mg
  • If needed tablets can be dispersed in water
    		•
    20 BENZBROMARONE Tablets 100 mg, 50mg 
  • FORM AND STRENGTH: 100mg Tablet
  • INDICATION: Gout where intolerant/allergic to allopurinol and febuxostat
  • DOSE: 100mg daily
  • PACK SIZE:
  • SUPPLIER: IDIS
  • LICENSE TYPE: Licensed in Germany

  • PRESCRIBING CONSULTANT: Dr Helen McIver (13/11/2013)
    		•
    13.06.01 Benzoyl Peroxide 
    13.06.01 Benzoyl Peroxide 5% with Clindamycin 1% Duac® Once Daily Cream
    12.03.01 Benzydamine Difflam® Oral rinse, Spray
    24.01 Benzyl penicillin  Indication:
    Empirical treatment of neonatal sepsis. Active againist streptococcal(including pneumococcal), gonococcal, and meningococcal infections
    Dose:
    50 mg/kg/dose bd
    Administration
    Slow IV bolus or infusion over 15–30 minutes. Longer administration time is particularly important when using doses of 50 mg/kg (or greater) to avoid CNS toxicity
    Dilute 600 mg in 5.7 mls = 100 mg/ml
    Monitoring
    Renal function
    Further Info:
    Consider reducing dose to 25mg/kg/dose in moderate to severe renal failure. Seek senior advice.
    Supply:
    Available from pharmacy as a stock item
    05.01.01.01 Benzylpenicillin Crystapen®
    05.01.01.01 Benzylpenicillin Benzathine 
    04.06 Betahistine Dihydrochloride  Tablet 8mg and 16mg
  • If needed tablets can be crushed and dispersed in water. More Info

    		•
    13.04 Betamethasone (as Dipropionate) 0.05% with Salicylic Acid 3% Diprosalic® Ointment, scalp lotion
    Potent
  • For thick plaque psoriasis
    		•
    13.04 Betamethasone (as Valerate) 0.025% Betnovate-RD® Cream, Ointment
  • Moderate
    • 13.04 Betamethasone (as Valerate) 0.1% Betnovate® Cream, Ointment, Scalp application, Lotion
  • Potent
    • 13.04 Betamethasone (as Valerate) 0.1% with Clioquinol Betnovate-C® Ointment, Cream
  • Potent with antimicrobial
    Now available generically but more expensive than before approx £19 for 30g
    		•
    13.04 Betamethasone (as Valerate) 0.1% with Neomycin Sulphate 0.5% Betnovate-N®
    12.01.01 Betamethasone 0.1% with Neomycin 0.5% ear drops 
    11.04.01 Betamethasone 0.1% with Neomycin 0.5% eye drops Betnesol N® Drops - Can be used for eye,ear and nose
    12.01.01 Betamethasone ear drops  Drops 0.1%
    11.04.01 Betamethasone eye ointment Betnesol® Eye ointment 0.1%
    11.04.01 Betamethasone eye, ear, nose drops Vistamethasone® Drops 0.1%- for the eye, ear & nose
    12.02.01 Betamethasone nasal drops  Drops 0.1%
    11.06 Betaxolol Betoptic® 0.5% Eye drops
    08.01.05 Bevacizumab Avastin®
    11.08.02 Bevacizumab intravitreal injection Avastin®
    02.12 Bezafibrate 
  • Immediate release tablets, 200mg
  • Modified release tablets, 400mg
    		•
    08.03.04.02 Bicalutamide 
    11.06 Bimatoprost Lumigan® Eye drops 0.01% and 0.03%
  • For those patients where pressure reduction has been inadequate on latanoprost


    		•
    11.06 Bimatoprost with Timolol Ganfort® Eye drops
    09.08.01 Biotin  
    06.01.01.02 Biphasic Insulin Aspart NovoMix® 30
    • 10mL vial, 3mL cartridge, 3mL prefilled pen
    06.01.01.02 Biphasic Insulin Lispro Humalog® Mix
  • Available as Mix25 and Mix50.
  • 3mL cartridge, 3mL prefilled pen (KwikPen)
    • 06.01.01.02 Biphasic Isophane Insulin Hypurin® Porcine 30/70 Mix
    06.01.01.02 Biphasic Isophane Insulin Humulin® M3
    • 10mL vial, 3mL cartridge, 3mL prefilled pen
    • First choice in type II diabetes
    06.01.01.02 Biphasic Isophane Insulin Insuman® Comb
  • Available as Comb 15, Comb 25, and Comb 50
    • 01.06.02 Bisacodyl  Tablet e/c 5mg, Suppository 10mg
    02.04 Bisoprolol  Tablet
  • First line use for heart failure
  • If needed tablets can be crushed and dispersed in water

    		•
    02.08.01 Bivalirudin  Injection (secondary care only)
  • Restricted to use in accordance with NICE TAG 230 and CG94. Consultant recommendation only.


    • 08.01.02 Bleomycin 
    08.02.03 Blinatumomab Blincyto®
  • For use in line with NICE TA450
    		•
    05.03.03 Boceprevir Victrelis®
    13.08.01 Borderline Substances Anthelios® Cream
  • Highest UVA/UVB protection
  • Preservative and perfume free
    		•
    08.01.05 Bortezomib Velcade®
    08.01.05 Bosutinib Bosulif®
    04.09.03 Botulinum Toxin Type A Botox® Prescribe by brand
  • Units are not equivalent
    		•
    04.09.03 Botulinum Toxin Type A Dysport® Prescribe by brand
  • Units are not equivalent
    		•
    04.09.03 Botulinum Toxin Type A Xeomin®
    08.01.05 Brentuximab vedotin Adcetris®
  • To be used in line with NICE guidance
    		•
    11.06 Brimonidine Tartrate  Eye drops 0.2%
    11.06 Brimonidine Tartrate 0.2% with Timolol 0.5% Combigan® Eye drops
    11.06 Brinzolamide Azopt® Eye drops 10mg/ml
    11.06 Brinzolamide 1% with Timolol 0.5%  Azarga® Eye drops
    13.05.03 Brodalumab Kyntheum

    To be prescribed as per NICE guidelines:

    TA511: Brodalumab for treating moderate to severe plaque psoriasis
    04.09.01 Bromocriptine 
    06.07.01 Bromocriptine  Tablets 1mg and 2.5mg
    01.05.02 Budesonide Budenofalk®
    • 3mg gastro resistant capsules
    01.05.02 Budesonide Jorveza®
    • 1mg orodispersible tablet
    • Restricted for use by gastroenterology only for eosinophilic oesophagitis
    01.05.02 Budesonide Cortiment
    • Cortiment 9mg prolonged release tablets
    • Once daily preparation
    01.05.02 Budesonide Entocort®
    • 3mg modified release capsules
    03.02 Budesonide Pulmicort® Dry powder inhaler, Nebules
  • Pulmicort turbohaler stocked at BTHFT, 100mcg/dose and 200mcg/dose
  • Easyhaler brand not stocked
  • Nebules 500mcg/2ml and 1mg/2ml
    		•
    12.02.01 Budesonide  Nasal spray 64micrograms per spray
    03.02 Budesonide and formoterol Symbicort®

    Dry powder inhaler (Turbohaler)

     
    02.02.02 Bumetanide  Tablet 1mg and 5mg, Liquid 1mg/5ml,
  • Liquid - very expensive. Tablets can be crushed and mixed with water as an alternative.
  • Injection 0.5mg/ml - no longer available, use furosemide IV if necessary
  • 1 mg oral bumetanide is roughly equivalent to 40 mg oral furosemide
    		•
    15.02 Bupivacaine Hydrochloride 
    15.02 Bupivacaine with Fentanyl 
    04.07.02 Buprenorphine BuTrans® patch Patch (Weekly patch)
  • Only for patients where other options eg codeine, tramadol or low dose morphine have been exhausted. Morphine preferred if a strong opioid needed.
  • When compared to other opiates Butrans® patches are weak and expensive

    • 04.07.02 Buprenorphine Temgesic®
    04.07.02 Buprenorphine Transtec® patch Patch
  • Change every 4 days (96 hours)
    		•
    04.10.03 Buprenorphine Subutex® Sublingual tablets 400mcg, 2mg and 8mg
    Substance misuse
  • Usual dose range 2-24mg

    Always confirm with patients substance misuse service or regular community pharmacy to confirm the dose before prescribing. Contact details for Bradford Substance Misuse:

    Bradford Substance Misuse Directory
    		•
    04.10.03 Buprenorphine and Naloxone Suboxone® Sublingual Tablets 2mg/0.5mg and 8mg/2mg
    Substance misuse
  • Usual dose range 2-24mg
    Always confirm with patients substance misuse service or regular community pharmacy to confirm the dose before prescribing. Contact details for Bradford Substance Misuse:

    Bradford Substance Misuse Directory
    		•
    04.10.02 Bupropion Hydrochloride Zyban®
    08.03.04.02 Buserelin 
    08.01.01 Busulfan 
    03.04.03 C1 Esterase Inhibitor Berinert®
    03.04.03 C1 esterase inhibitor Cinryze®
    08.01.05 Cabazitaxel Jevtana® Available Via CDF for following

  • 2nd line treatment of advanced castration resistant prostate cancer following docetaxel based regimen

  • 3rd line treatment of advanced castration resistant prostate cancer following docetaxel and abiraterone based treatment
    		•
    04.09.01 Cabergoline 
    06.07.01 Cabergoline  Tablets 500microgram
    24.01 Caffeine CITRATE  Indication:
    Neonatal apnoea
    Dose:
    Loading - 20mg/kg OD
    Maintenance - 10 mg/kg od
    In some cases 40mg/kg loading and 20mg/kg OD maintenance may be used – D/W Consultant
    Administration
    Oral or IV
    IV infusion over 30 mins in 5% dextrose.
    Dilute 5ml of Caffeine Citrate (10mg/ml) in 5ml Glucose 5% = 5mg/ml
    Monitoring
    Levels (not routinely needed) 75-150 mmol/litre
    Further Info:
    Caffeine:prescribed as CAFFEINE CITRATE only
    Supply:
    Available from pharmacy as stock
    13.03 Calamine  lotion, with aqueous cream
    13.05.02 Calcipotriol Dovonex®
    13.05.02 Calcipotriol 50micrograms/g with Betamethasone 0.05% Dovobet® Gel, Ointment
    06.06.01 Calcitonin (salmon) / Salcatonin  Injection
    09.06.04 Calcitriol 
    13.05.02 Calcitriol 3micrograms/g Silkis®
    09.05.02.02 Calcium Acetate Phosex® Tablets
  • Generally recommended as first line phosphate binder. More effective than calcichew and less elemental calcium.
    • 09.05.02.02 Calcium Carbonate  Tablets
  • Calcium-based phosphate binders may be used as the initial binder therapy for patients with chronic kidney disease as they are cheap and relatively efficacious, in conjunction with dietary phosphate restriction, to control phosphorus and parathyroid levels.
  • If hypercalcaemia develops with the use of calcium carbonate, it may be necessary to convert to calcium acetate, a non calcium-containing phosphate binder, or a combination of both.
    • 09.05.01.01 Calcium Chloride  Injection 10%
    Acute treatment of hypocalcaemia, see local guidance
    08.01 Calcium Folinate 
    09.05.01.01 Calcium Gluconate  Injection 10%
  • Ca2+ approx 225micromol/ml
    		•
    09.05.02.02 Calcium salts with magnesium carbonate Osvaren®
    09.05.01.01 Calcium-Sandoz®  Syrup - CURRENT SUPPLY ISSUES ALTERNATIVES INCLUDE CACIT EFFERVESCENT TABLETS AND SANDOCAL
  • calcium glubionate 1.09 g, calcium lactobionate 727 mg (calcium 108.3 mg or Ca2+ 2.7 mmol)/5 mL
    • 02.05.05.02 Candesartan  Tablets
  • If needed tablets can be crushed and dispersed in water
    		•
    13.09 Capasal® 
    08.01.03 Capecitabine Xeloda®
    04.07.03 Capsaicin 
    10.03.02 Capsaicin Zacin®
    10.03.02 Capsaicin Qutenza®
    02.05.05.01 Captopril  Tablet, Liquid (5mg/ml and 25mg/ml

  • If needed tablets disperse in water. Flush enteral tubes well after administration.
    NB: Absorption may be reduced if given via enteral tube that terminates in the jejunum.
    • 24.01 Captopril  Indication:
    Congestive cardiac failure and hypertension
    Dose:
    Initailly a test dose 10 mcg/kg,
    If tolerated increasing to max dose of 100mcg/kg/dose tds.
    Older babies require a larger dose, see BNF-C
    Administration
    Oral
    Monitoring
    Close monitoring of blood pressure essential
    Renal function
    Further Info:
    Also used to reduce proteinuria in nephrotic syndrome
    Supply:
    Available from pharmacy as a named pateint.
    04.02.03 Carbamazepine  Tablets 100mg, 200mg, 400mg
    Slow relase preparations also available
    Liquid 100mg/5ml
  • Usual dose range 400mg-600mg two to three times daily
  • Max daily dose 1600mg

    		•
    04.07.03 Carbamazepine 
    04.07.03 Carbamazepine 
    04.08.01 Carbamazepine 
    04.08.01 Carbamazepine Tegretol®
    04.08.01 Carbamazepine Carbagen® SR
    04.08.01 Carbamazepine Tegretol® Retard
    06.02.02 Carbimazole Neo-Mercazole® Tablets 5mg and 20mg
    03.07 Carbocisteine  Capsules 375mg, Liquid 125mg/5ml and 250mg/5ml
    11.08.01 Carbomer 980 eye drops  Viscous eye drops (gel)
    08.01.05 Carboplatin 
    07.01.01 Carboprost Hemabate® Injection- secondary care only
    09.08.01 Carglumic Acid Carbaglu®
    11.08.01 Carmellose  Eye drops - unit dose 0.5% and 1%
  • Xailin Fresh formulary product for 0.5% unit dose drops
    • 08.01.01 Carmustine BiCNU®
    08.01.01 Carmustine Gliadel®
    09.08.01 Carnitine Carnitor®
    A2.05.02 Carobel, Instant®  
  • For use in infants under 1 year
    		•
    02.04 Carvedilol  Tablet
    07.04.04 Catheter Patency Solutions 
  • Sodium chloride 0.9%
  • Solution G
    		•
    05.01.02.01 Cefaclor 
    05.01.02.01 Cefalexin 
    05.01.02.01 Cefotaxime 
    24.01 CefoTAXime  Indication:

    Dose:
    50mg/kg/dose bd in <7days
    50mg/kg/day tds in >7days
    Administration
    IV bolus/infusion
    Monitoring
    Renal function-consider dose reduction in severe renal failure.Consider 25mg/kg BD
    Further Info:
    Cephalosporins are not active against enterococci, listeria, campylobacter or clostridia
    Supply:
    Available as stock from pharmacy
    05.01.02.01 Cefradine 
    05.01.02.01 Ceftaroline Zinforo®
    24.01 CefTAZidime  Indication:
    Infection-
    Dose:
    50 mg/kg/dose bd
    Reduce dose in renal failure
    Administration
    Infuse over 30 mins
    Dilute 500mg in 4.5 mls = 100mg/ml
    Monitoring
    Renal function
    Further Info:
    Remember cephalosporins are not active against enterococci, listeria, campylobacter or clostridia
    Supply:
    Available from DSU as stock syinges
    05.01.02.01 Ceftazidime with avibactam 
    • For intiation by microbiology or infecious diseases team only
    05.01.02.01 Ceftriaxone 
    05.01.02.01 Cefuroxime 
    11.03.01 Cefuroxime   Unlicensed - prepared by aseptic unit
    13.05.03 Certolizumab  Cimzia

    As per NICE guidelines:

    TA445: Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs

    TA574: Certolizumab pegol for treating moderate to severe plaque psoriasis
    10.01.03 Certolizumab Pegol Cimzia®
  • For use in line with NICE guidance
    		•
    12.01.03 Cerumol®  Ear drops
    (Chlorobutanol 5%, Pardichlorobenzene 2%, Arachis (peanut) oil 57.3%)
    Contains peanut oil

    03.04.01 Cetirizine  Tablet 10mg, Liquid 1mg/ml
    13.02.01 Cetraben®  Cream and Bath oil
    13.02.01.01 Cetraben®Bath additive  Bath additive
    13.11.03 Cetrimide 
    08.01.05 Cetuximab Erbitux®
  • Available Via CDF
  • KRAS testing to be carried out before initiation. Test also funded by the CDF
  • For use in line with NICE TAs 145, 242 and 439
  • Patient Access Scheme available for this treatment (in line with NICE TA439)

    		•
    04.01.01 Chloral Hydrate  Tablets, cloral betaine 707 mg (≡ chloral hydrate 414 mg),
    Liquid chloral hydrate 143.3 mg/5 mL
  • Alternative for insomnia
  • Usual dose range 1-2 tablets at night or 15-45mls Liquid
  • Max daily dose 5 tablets or 70ml liquid
  • Max single dose 5 tablets or 70ml liquid

    		•
    24.01 Chloral Hydrate  Indication:
    Short term sedation
    Dose:
    10-30 mg/kg/dose tds
    reduce dose in mild to moderate hepatic impairment
    Administration
    Oral
    Monitoring
    LFT and U&E
    Further Info:
    May accumulate with repeated doses.
    Avoid in severe renal and hepatic impariment
    Supply:
    Available from pharmacy as a liquid(143mg in 5ml)
    08.01.01 Chlorambucil 
    05.01.07 Chloramphenicol  Ear and eye only
    11.03.01 Chloramphenicol  Eye drops 0.5%, Eye ointment 1%, Minims 0.5% (preservative free)
  • Unlicensed use - topically to wound sutures and for bites
    		•
    12.01.01 Chloramphenicol  Ear drops 5% and 10%
    04.01.02 Chlordiazepoxide  Capsules 5mg and 10mg
    24.01 Chlorhexidine 
  • This is our preferred antisepsis for procedures such as long lines, umbilical lines and LPs etc.
  • strength 0.5%
    • 12.03.04 Chlorhexidine Gluconate Corsodyl®
    13.11.02 Chlorhexidine gluconate 4%  Hibiscrub®

    Skin antisepsis

    • MRSA suppression: use once daily for duration of admission
    12.03.02 Chlorhexidine Mouthwash 
    10.01.03 Chloroquine  Tablet,Syrup.
    02.02.01 Chlorothiazide  Tablets Not stocked at BTHFT
    Restricted Item Suspension for paediatric use 250mg/5ml
    24.01 Chlorothiazide  Indication:
    Heart failure, hyperinsulinaemic hypoglycaemia and chronic lung disease
    Dose:
    10 mg/kg/dose bd
    Administration
    Oral
    Monitoring
    U&E
    Renal function
    Further Info:
    May cause hypokalaemia and hyperuricaemia
    Supply:
    Available from pharmacy as a named patient request. 250mg in 5ml(50mg/ml)liquid
    03.04.01 Chlorphenamine  Tablets 4mg. Liquid 2mg/5ml, Injection

  • can cause drowsiness
    		•
    04.02.01 Chlorpromazine  Tablet 25mg, 50mg, 100mg Oral solution 25 mg/5 mL
  • First generation antipsychotic
  • Usual dose range: 75-300mg in divided doses
  • Max daily dose: 1000mg
  • Max single dose: not stated
    		•
    24.01 Chlorpromazine  Indication:
    Neonatal abstinence syndrome
    Dose:
    Up to1 mg/kg/dose tds
    Administration
    Oral
    Monitoring
    Blood pressure
    Further Info:
    Dose can be doubled in severe withdrawal. Maximum dose 6mg/kg/day
    Supply:
    Available from pharmacy as a named patient, 25mg in 5ml oral liquid (5mg/ml)
    04.06 Chlorpromazine Hydrochloride 
    12.03.01 Choline Salicylate Bonjela® Adult For use in adults and children over 16
    06.05.01 Chorionic Gonadotrophin Pregnyl® Injection 5000 unit ampoule
    03.02 Ciclesonide Alvesco® Aerosol Inhaler
  • 80mcg/dose stocked at BTHFT
    		•
    01.05.03 Ciclosporin  Injection 50mg/ml, capsules 10mg. 25mg and 50mg, liquid 100mg/ml- secondary care only

    Ciclosporin must be prescribed by brand - Neoral stocked at BTHFT
    08.02.02 Ciclosporin Capimune®, Neoral®
    08.02.02 Ciclosporin 
    10.01.03 Ciclosporin 
    11.99.99.99 Ciclosporin  Eye drops 0.05%
  • Unlicensed
    		•
    13.05.03 Ciclosporin Capimune

    Prescribed by brand

    SWYAPC shared care guidelines
    11.99.99.99 Ciclosporin 0.1% eye drops Verkazia®
    • 0.3ml unit dose eye drops
    • Paediatric opthalmology use only
    11.99.99.99 Ciclosporin 0.1% eye drops Ikervis®
    • 0.3ml unit dose eye drops
    • Adult opthalmology use only
    09.05.01.02 Cinacalcet  Tablets 30mg, 60mg and 90mg
    04.06 Cinnarizine  Tablets 15mg
    05.01.12 Ciprofloxacin 
    11.03.01 Ciprofloxacin  Eye drops 0.3%
    12.01.01 Ciprofloxacin 
    20 Cisapride 
  • FORM AND STRENGTH: Tablets 10mg
  • INDICATION: Prokinetic
  • DOSE: 10mg three to four times daily
  • PACK SIZE:
  • SUPPLIER:
  • LICENSE TYPE:

    PRESCRIBING CONSULTANT:

    DATE AUTHORISED:
    • 08.01.05 Cisplatin 
    04.03.03 Citalopram  Tablets 10mg, 20mg and 40mg
    Oral drops 40mg/ml, 4 drops (8mg) equivalent to 10mg tablet
  • Usual dose range 20-40mg daily
  • Max daily dose 40mg
  • Max single dose 40mg
    		•
    01.06.04 Citrate micro enema  Micro-enema
    08.01.03 Cladribine Litak®
    08.01.03 Cladribine 
    05.01.05 Clarithromycin 
    05.01.06 Clindamycin 
    07.02.02 Clindamycin Dalacin® Cream 2%, 40g pack with 7 applicators
    13.06.01 Clindamycin 1% Dalacin T® Lotion
    04.08.01 Clobazam 
    13.04 Clobetasol Propionate (with antimicrobials) Dermovate-NN® Ointment, Cream
  • Very Potent with antimicrobial
    Now available generically but more expensive than before approx £64.00

    		•
    13.04 Clobetasol Propionate 0.05% Dermovate® Cream, Ointment, Scalp application, Shampoo (Etrivex®)
    Very potent
  • Prescribe by brand name (hospital only)to avoid confusion between similar sounding generic names
    		•
    13.04 Clobetasone Butyrate 0.05% Eumovate® Cream, Ointment
    Moderately potent
  • Prescribe by brand name (hospital only)to avoid confusion between similar sounding generic names


    		•
    13.04 Clobetasone butyrate 0.05%, oxytetracycline 3%, nystatin 100,000units/g Trimovate®
  • Ongoing supply problem
    Cream
    Contains:Clobetasone Butyrate 0.05%, Oxytetracycline 3%, Nystatin 100,000 units/g
  • Moderately potent with antimicrobials
    • 08.01.03 Clofarabine Evoltra® VIA CDF for following

    Acute lymphoblastic leukaemia in patients with relapsed/ refractory disease in whom the intent is to use treatment as a bridge to bone marrow transplantation

    Acute Myeloblastic leukaemia in patients with relapsed/ refractory disease in whom the intent is to use treatment as a bridge to bone marrow transplantation
    04.01.01 Clomethiazole Heminevrin® Cspsules 192mg clomethiazole base
    alternative for insomnia
  • Usual dose range: 1-2 capules at night
  • Max daily dose 2 capsules
  • Max single dose 2 capsules
    		•
    06.05.01 Clomifene Citrate  Tablets 50mg
    04.03.01 Clomipramine  Capsules 10mg, 25mg, 50mg, 100mg Tablets m/r 75mg
  • Usual dose range 30-150mg in divided doses
  • Max daily dose 250mg
  • Max single dose 250mg
    		•
    04.02.03 Clonazepam 
    04.08.01 Clonazepam 
    04.08.02 Clonazepam  Injection 1mg/ml
    Management of disturbed befaviour
  • Max daily dose 500mcg to 2mg (6mg in 24 hours)
  • max single dose 2mg
    		•
    24.01 Clonazepam  Indication:
    Continuous severe seizures resisant to routine anticonvulsants.
    Dose:
    IV bolus 100 mcg/kg/dose once daily.
    IV infusion 10 /kg/hour has been used in older babies increasing to 60micrograms/kg/hr if necessary
    Administration
    Slow IV injecition over 2-3minutes
    Monitoring
    Respiration
    Salivary and bronchial hypersecretion.
    Further Info:
    Prolonged infusion may lead to accumulaiton and delay recovery
    Can be reversed by flumazenil 20 mcg/kg IV- may need repeat doses
    Supply:
    Available from pharmacy as a stock item
    02.05.02 Clonidine Hydrochloride 
    02.09 Clopidogrel  Tablet
  • If needed tablets can be dispersed in water.
    • 07.02.02 Clotrimazole  Cream 1%, Pessaries 500mg, 200mg and 100mg
  • 2% cream not stocked at BTHFT, 1% cream as effective for relief of external thrush symptoms
    		•
    12.01.01 Clotrimazole Canesten® Solution 1%
    13.10.02 Clotrimazole 
    04.02.01 Clozapine Clozaril® HOSPITAL ONLY
  • To be initiated by consultant psychiatrist only. For treatment-resistant schizophrenia

    Tablets 25mg and 100mg
  • Usual dose range: Adjustable initial titration (CPMS blood tests) 200-450mg
  • Max daily dose: Max 900mg
    		•
    04.02.01 Clozapine Denzapine® CLOZARIL brand used within BTHFT
    04.02.01 Clozapine Zaponex® CLOZARIL brand used within BTHFT
    13.09 Coal Tar Extract 5% (Alcoholic) Alphosyl 2 in 1®
    13.05.02 Coal Tar in Lassars Paste  2%, 4% & 5%
    13.05.02 Coal tar lotion 5% Exorex® Lotion
    02.02.04 Co-amilofruse (furosemide and amiloride)  Tablets
  • If needed tablets can be dispersed in water
    		•
    05.01.01.03 Co-Amoxiclav 
    05.01.01.03 Co-Amoxiclav Augmentin®
    04.09.01 Co-Beneldopa Madopar®CR
    04.09.01 Co-Beneldopa Madopar®
    11.07 Cocaine  specialist use only
    4% eye drops
    04.09.01 Co-Careldopa Sinemet® CR
    04.09.01 Co-Careldopa Sinemet®
    04.09.01 Co-Careldopa Half Sinemet ®CR
    04.09.01 Co-Careldopa and Entacapone Stalevo®
    13.06.02 Co-Cyprindiol 2000/35
    (Cyproterone Acetate 2mg with Ethinylestradiol 35micrograms)     Dianette®
    01.06.02 Co-danthramer  Capsule 25/200mg, Suspension 25/200mg/5ml
  • Generally restricted for use in terminally ill patients

  • can colour the urine red
    		•
    01.06.02 Co-danthrusate 
    01.04.02 Codeine  Tablets 15mg, 30mg, 60mg and syrup (25mg/5ml)
    04.07.02 Codeine analgesia Tablet, Syrup (25mg/5mL), Injection (not recommended as no advantages over morphine and is a CD)
    10.01.04 Colchicine 
    09.06.04 Colecalciferol 

    Colecalciferol preparations supplied for treatment of deficency only

    • Plenchol 20,000 unit capsules
    • Thorens 10,000 unit/ml oral drops- for children and adults with swallowing difficulties
    • Maintenance doses (e.g. 1000 unit capsules) not stocked
    02.12 Colesevelam 
    01.09.02 Colestyramine  Powder sachets
    02.12 Colestyramine 
  • Questran®
  • Questran Light®- sugar free
    		•
    05.01.07 Colistimethate Promixin® Nebulules.
  • Nebuliser solution for use with I-neb nebuliser
  • Work on repatriation of these treatments to secondary care is under discussion with NHS England. Until this work is concluded, GPs should continue to supply under shared care arrangements
    		•
    05.01.07 Colistimethate for nebulisation Colomycin®
    10.03.01 Collagenase Xiapex®
    06.04.01.01 Combined continuous HRT tablet Premique ®
  • Premique® low dose tablet

    • 06.04.01.01 Combined cyclical HRT tablet Elleste-Duet®, Prempak-C®
    07.03.01 Combined Hormonal Contraceptives Evra Patches - Ethinylestradiol with Norelgestronim
  • One patch to be applied weekly for 3 weeks followed by a 7 day patch-free interval
    		•
    07.03.01 Combined Hormonal Contraceptives TriNovum®
    09.02.02.01 Compound Sodium Lactate Intravenous Infusion 
  • Hartmann's Solution 500ml or 1 litre
  • Half Strength Hartmann's Solution
  • Dextrose 5% & Half Strength Hartmann's Solution 500ml polyfusor
  • Hartmann's Solution = Sodium Chloride 0.6%, Sodium Lactate 0.25%, Potassium Chloride 0.04%, Calcium Chloride 0.027%
    • 01.04.02 Co-Phenotrope Lomotil® Tablet
  • contains diphenoxylate 2.5mg and atropine 25 microgrames
    		•
    05.01.08 Co-trimoxazole 
    08.01.05 Crisantaspase Erwinase®
    08.01.05 Crizotinib Xalkori®
    13.03 Crotamiton Eurax®
    04.06 Cyclizine  Tablets 50mg
    11.05 Cyclopentolate Hydrochloride 
  • Mydrilate® 0.5% and 1% eye drops
  • Minims® Cyclopentolate Hydrochloride 0.5% and 1% single use eye drops
    		•
    08.01.01 Cyclophosphamide 
    06.04.02 Cyproterone Acetate  Tablet 50mg
    08.03.04.02 Cyproterone Acetate 
    08.01.03 Cytarabine DepoCyte®
    08.01.03 Cytarabine 
    02.08.02 Dabigatran  Capsules 75mg, 110mg and 150mg

    Rivaroxaban is the oral anticoagulant of choice for prophylaxis of VTE following total knee and hip replacement

    POSITION STATEMENT TO ADD IN REGARDS TO ROLE IN STROKE AND AF
    08.01.05 Dacarbazine 
    08.02.02 Daclizumab Zenapax®
    08.01.02 Dactinomycin Cosmegen Lyovac®
    24.01 Dalivit  0.6mls once daily O/NG
    02.08.01 Danaparoid  Injection 1250units/ml

    Can be used as an alternative in patients who have developed heparin-induced thrombocytopenia (HIT)
    06.07.02 Danazol  Capsules 100mg, 200mg
    10.02.02 Dantrolene 
    15.01.08 Dantrolene Sodium 
    09.01.03 Darbepoetin Alfa  Injection:
    - Prefilled syringes
    - Prefilled disposable injection device (Aranesp®SureClick)

    07.04.02 Darifenacin Emselex® Tablet 7.5mg and 15mg
    05.03.01 Darunavir Prezista®
    08.01.05 Dasatinib Sprycel®
    08.01.02 Daunorubicin 
    09.01.03 Deferasirox  Dispersible tablet
    09.01.03 Deferiprone  Tablet
    06.03.02 Deflazacort Calcort® Tablet 6mg
    08.03.04.02 Degarelix Firmagon®
    06.06.02 Denosumab XGEVA®
  • See denosumab (Prolia®) for drug saftey information
    		•
    06.06.02 Denosumab Prolia®
    13.08.02 Dermacolor® 
    13.02.01 Dermol® 
    18 Desferrioxamine 
    09.01.03 Desferrioxamine Mesilate 
    15.01.02 Desflurane Suprane®
    24.02 Designer Fluids  See Link
    03.04.01 Desloratadine Neoclarityn® Tablets 5mg
    06.05.02 Desmopressin  Noqdirna® Sodium should be monitored at 7 days and 1 month after starting
    06.05.02 Desmopressin  DDAVP: Tablet, Nasal spray, Sublingual tablet , Injection 4mcg/ml.
    Indicated for diabetes insipidus or polyuria/polydypsia. Usually tds.
    Water Deprivation test single dose - see protocol below

    Desmotabs: Indicated for primary nocturnal enuresis. Usually once daily.

    Octim: Injection 15mcg/ml - For bleeding episodes in responding patients with mild haemophilia A, Von Willebrands Disease and platelet function disorders. (Nasal spray Non-Formulary)
    06.03.02 Dexamethasone  Tablets 0.5mg, 2mg, oral solution 2mg/5ml

  • Dexamethasone 2mg/5ml liquid is used for 500mcg and 1mg doses of dexamethasone
  • Dexamethasone 2mg Tablets are used for doses 2mg and above

    		•
    24.01 Dexamethasone  Indication:
    Ventilator dependent chronic lung disease(CLD)
    Dose:
    Prescribe as Dexamethasone Base
    Individualised dosing after discussion with consultant.
    Doses have ranged from 50micrograms/kg/day to 500micrograms/kg/day in divided doses.
    See Neonatal Formulary for further information
    Administration
    IV
    Monitoring
    Blood sugars, Blood pressure, Renal function, Liver function, GI side effects
    Further Info:
    IV may be diluted in sodium chloride 0.9% or glucose 5% to aid administration
    Supply:
    Available from pharmacy as a stock item
    11.04.01 Dexamethasone eye drops  Eye drops 0.1% and single dose minims 0.1%
    11.04.01 Dexamethasone intravitreal implant Ozurdex®
    12.01.01 Dexamethasone with Antibacterial Otomize® Ear spray
    (Dexamethasone 0.1%, Neomycin Sulphate 3250 units per mL and Glacial Acetic Acid 2%)
    12.01.01 Dexamethasone with Antibacterial Sofradex® Drops (Dexamethasone 0.05%, Framycetin Sulphate 0.5%, Gramicidin 0.005%)
  • Treatment of otitis externa
    		•
    11.04.01 Dexamethasone with Antibacterials Sofradex® Drops (ear or eye)
  • Dexamethasone (as sodium metasulphobenzoate) 0.05%
  • Framycetin sulfate 0.5%
  • Gramicidin 0.005%
    		•
    11.04.01 Dexamethasone with Neomycin and Polymyxin B sulphate Maxitrol® Eye drops, Eye ointment
  • Generally prescribed post surgery
    		•
    04.04 Dexamfetamine  Tablets 5mg
  • Drug treatment of Attention Deficit Hyperactivity Disorder (ADHD)
  • Usual dose range 2.5mg - 5mg TDS (1mg/kg)
  • max daily dose 20mg
  • max single dose 5mg
    		•
    15.01.04.04 Dexmedetomidine  
    04.07.02 Diamorphine  Injection
    04.01.02 Diazepam  Tablets 2mg, 5mg and 10mg. Oral suspension 2mg/5ml
  • Usual dose range: 2-10mg three times daily
  • Max daily dose 30mg
  • Max single dose 10mg
    		•
    04.08.02 Diazepam 
    10.02.02 Diazepam  Tablets 2mg, 5mg, 10mg
    Liquid 2mg/5ml
    15.01.04.01 Diazepam 
    24.01 Diazepam  Indication:
    Sedation and Seizures
    Dose:
    200micrograms/kg/dose repeated after 10 minutes if necessary
    Administration
    Slow IV bolus
    Monitoring
    hypotension, apnoea, respiratory depression, urinary retention,gastro-intestinal disturbances
    Further Info:
    Use Diazemuls as less irritant.
    Reversed by flumazenil 20 mcg/kg IV- may need repeat doses
    Supply:
    Available from pharmacy as a stock item
    06.01.04 Diazoxide Eudemine®
  • For specialist use only
    		•
    10.01.01 Diclofenac 

    Following Drug Safety Updates the use of diclofenac is restricted to use where the risks and benefits of continued treatment have been considered (see MHRA Drug Safety Updates below)

    • Suppositories available: 12.5mg, 25mg, 50mg, 100mg
       
    11.08.02 Diclofenac Voltarol® Ophtha
    13.08.01 Diclofenac Solaraze®
    11.08.02 Diclofenac Sodium Voltarol® Ophtha multidose
    18 Dicobalt edetate 
    01.02 Dicycloverine  Tablets 10mg and 20mg, Liquid 10mg/5ml
    08.03.01 Diethylstilbestrol 
    02.01.01 Digoxin  Tablets 62.5mcg, 125mcg and 250mcg, Elixir 50mcg/ml, Injection 250mcg/ml (secondary care only)
  • Bioavailability’s are approximately: Injection 100%, Liquid 80%, Tablets 70%
    		•
    24.01 Digoxin  REVIEW?
    Indication:
    Supraventricular tachycardia
    Dose:

    Total loading dose
    given as ½ immediately
    ¼ at 8 hours
    ¼ at 16 hours
    >2.5kg total loading dose:
    IV = 35 micrograms/kg
    oral = 45 micrograms/kg
    >2.5kg oral maintenance dose:
    10 micrograms/kg od
    For low birth weight babies see Neonatal Formulary
    Administration
    IV or Oral
    Monitoring
    Potassium, renal function, arrhythmias, conduction disturbances, thrombocytopenia.
    The plasma-digoxin concentration should be maintained in the range 0.8–2 micrograms/litre. Blood should be taken at least 6 hours after a dose
    Further Info:
    Hypokalaemia predisposes the child to digitalis toxicity.
    Supply:
    Available from pharmacy as a named pateint.
    Liquid suppled as 50micrograms in 5mls (10micrograms/ml)
    Always check dose carefully because an overdose can cause death.
    02.01.01 Digoxin specific antibody fragments Digifab®
  • DigiFab® replaces Digibind® (Dec 2011).
  • Click here for Digifab SPC
  • Very rarely needed and extremely expensive. Discuss with the National Poisons Centre (08448920111) first, then with Medicines Information (4598) or the on call pharmacist (via switchboard after 17:30).
  • Toxbase website here
    		•
    04.07.02 Dihydrocodeine  Tablet, Tablet MR, Oral solution, injection
  • Injection is a CD
    		•
    02.06.02 Diltiazem  Tablets, Capsules
  • Prescribe by brand according to medicines policy
    		•
    01.07.04 Diltiazem Cream 2%  Unlicensed - available for patients unresponsive or intolerant to GTN ointment

    Dose 2cm twice daily, store in fridge , 1 tube lasts one month
    13.05.03 Dimethyl fumarate Skilarence

    As per NICE guidelines:

    TA475: Dimethyl fumarate for treating moderate to severe plaque psoriasis
    13.10.04 Dimeticone Hedrin®
    07.01.01 Dinoprostone Propess® Pessaries releasing 10mg over 24 hours
    07.01.01 Dinoprostone Prostin E2® IV solution 1mg/ml
    Injection
    Vaginal tablet (Prostin E2)
    13.02.01 Diprobase®  Cream, Ointment
    02.09 Dipyridamole  Capsule MR
  • Secondary prevention of ischaemic stroke and TIA normally in combination with aspirin for existing patients and those unable to take clopidogrel
  • If needed capsules can be opened and beads mixed with water (do not crush). Flush enteral tubes well as there is potential for blockage.
    • 11.99.99.99 Disodium Edetate 0.37%   Solution 20mL (preservative free) (Unlicensed Product)
    20 Disodium Edetate 0.37% eye drops EDTA Solution 20ml (preservative free) (Unlicensed Product)
  • Specialist use only
  • Unlicensed request signed by Helen Devonport on behalf of Nigel James 11/06/2014
  • Treatment of Calcific Band Keratopathy
    		•
    06.06.02 Disodium Pamidronate  injection
    02.03.02 Disopyramide  Capsule, Tablet MR, Injection (secondary care only)
    13.05.02 Dithranol Dithrocream® Cream 0.1%
    Cream 0.25%
    Cream 0.5%
    Cream 1%
    Cream 2%
    13.05.02 Dithranol Ointment BP 
    13.05.02 Dithranol Paste BP 
    02.07.01 Dobutamine  Infusion (secondary care only)

    24.01 DoBUTamine  Indication:
    Hypotension
    Dose:
    5-20 micrograms/kg/min
    Infusion at 1ml/kg/hr = 20microg/kg/min
    Prescribe concentration, rate and dose
    Administration
    Infusion
    Monitoring
    Blood pressure(marked increase in systolic blood pressure indicates overdose)
    arrhythmias,dyspnoea, bronchospasm and hypokalaemia
    Further Info:
    Compatibility: May be added (terminally)to Adrenaline, Amiodarone, Dopamine, Fentanyl, Heparin, Magnesium sulphate, Milrinone, Morphine sulphate, noradrenaline and Potassium chloride
    Supply:
    Available from pharmacy as a standard stock syringes containing 60mg in 50mls(1200micrograms/ml). Pharmacy can also supply 120mg in 50ml(2400micrograms/ml) as a named patient
    08.01.05 Docetaxel Taxotere®
    01.06.02 Docusate Sodium  Capsule 100mg, Solution 50mg/5ml (adult) 12.5mg/5ml (paediatric)
    04.06 Domperidone  Tablet, Suspension, Suppository
  • See link below for MHRA advice about dose restrictions and contraindications

    		•
    04.11 Donepezil  Tablet 5mg, 10mg
  • First Line for Mild to moderate Alzheimers disease
  • usual dose range 5-10mg at night
  • max daily dose 10mg at night
  • Max single dose 10mg
    		•
    02.07.01 Dopamine  Infusion (secondary care only)

    24.01 DoPAmine  Indication:
    Hypotension
    Dose:
    2-20 micrograms/kg/min.
    Infusion at 1ml/kg/hr = 20microg/kg/min.
    Prescribe concentration, rate and dose
    Administration
    Infusion via central line
    Monitoring
    Blood pressure
    U&E
    Peripheral perfusion
    Further Info:
    Compatibility: May be added (terminally)to Adrenaline, Amiodarone, Dobutamine, Fentanyl, Heparin, Magnesium sulphate, Milrinone, Morphine sulphate and Potassium chloride.
    Central line infusion via filter avoids danger of tissue ischaemia
    Supply:
    Available from pharmacy as a standard stock syringes 60mg in 50mls(1200micrograms/ml). Pharmacy can supply 120mg in 50mls (2400micrograms/ml) as a named patient
    02.07.01 Dopexamine  Infusion (secondary care only)

    03.07 Dornase Alfa Pulmozyme® Nebuliser Solution 2.5ml (pack size 30)

  • Expensive item, store in the fridge
  • Work on repatriation of these treatments to secondary care is under discussion with NHS England. Until this work is concluded, GPs should continue to supply under shared care arrangements
    		•
    11.06 Dorzolomide  Eye drops 2%
    11.06 Dorzolomide 2% with Timolol 0.5% Cosopt® Eye drops
    04.03.01 Dosulepin  Tablets 75mg Capsules 25mg
  • Usual dose range 75-225mg
  • Max daily dose 225mg
  • Max single dose 225mg in one to three divided doses
    		•
    13.02.01 DoubleBase®  Doublebase gel
    Dayleve gel (can be used less often than doublebase original, twice daily)
    Shower gel
    03.05.01 Doxapram Dopram® Injection
    15.01.07 Doxapram Dopram®
    24.01 Doxapram  Indication:
    Respiratory depression where severe apnoea is refractory to caffeine
    Dose:
    2.5 mg/kg loading dose over 10 minutes then 0.3-1 mg/kg/hour.
    Administration
    IV infusion
    Monitoring

    Further Info:
    A few babies need more but watch for neurotoxicity
    50mg (2.5ml)/kg of stock solution diluted to 50mls 1ml/hr = 1mg/kg/hr
    Supply:
    Available from pharmacy as a stock item
    02.05.04 Doxazosin  Tablet, Tablet MR
  • May be used as a 4th line option in the management of hypertension when control has not been achieved with other agents.
    • 07.04.01 Doxazosin 
    04.03.01 Doxepin 
    13.03 Doxepin Hydrochloride Xepin®
    08.01.02 Doxorubicin Hydrochloride 
    08.01.02 Doxorubicin Hydrochloride Caelyx®
    05.01.03 Doxycycline 
    05.04.01 Doxycycline 
    02.03.02 Dronedarone Multaq® Tablets
  • Restricted for cardiologist initiation in accordance with NICE guidance (TA197).
    • 04.06 Droperidol Xomolix® For use by ICU and theatres only
    03.01.05 Drug Delivery Device Haleraid® For use with MDI pressurised inhalers to aid when strength in hands is impaired (eg in arthritis)
    03.01.05 Drug Delivery Device Volumatic® Large volume device for adults and children
  • available with a paediatric mask
    • 03.01.05 Drug Delivery Device AeroChamber Plus®
  • Adult and children > 5 years = Blue (+/- mask)
  • Child 2-5 years = Yellow
  • Infant (6 months - 2 years) = Orange
    • 03.01.05 Drug Delivery Device Babyhaler® for paediatric use
    06.01.02.03 Dulaglutide Trulicity® 0.75mg/0.5ml & 1.5mg/0.5ml pre-filled pen/pre-filled syringe

  • Restricted for initiation by diabetes team
    		•
    04.03.04 Duloxetine Cymbalta® Capsules 30mg and 60mg
  • Usual dose range 60mg daily
  • Max daily dose 60mg
  • Max single dose 60mg
    		•
    04.03.04 Duloxetine Yentreve®
    04.03.04 Duloxetine Cymbalta® Capsules 30mg and 60mg
  • Usual dose range 30-60mg daily
  • Max daily dose 120mg
  • Max single dose 120mg
    		•
    07.04.02 Duloxetine Yentreve® Capsule 20mg and 40mg
    13.08.01 Dundee reflective sun creams Dundee Block®
    13.05.03 Dupilumab Dupixent®

    To be used accordingly to NICE guidelines:

    TA534: Dupilumab for treating moderate to severe atopic dermatitis
    06.04.02 Dutasteride Avodart® Capsule 500micrograms
    06.04.01.02 Dydrogesterone Duphaston®
    13.02.01 E45®  Cream, Lotion, Wash emmolient
    24.01 Edrophonium  Tensilon REVIEW??

  • 20 mcg/kg then after 30 secs a further 80 mcg/kg
  • Keep atropine ready
  • Monitor ECG
    		•
    10.02.01 Edrophonium Chloride 
    09.01.04 Eltrombopag  Tablet
    11.04.02 Emedastine Emadine® Eye drops 0.05%
    13.02.01.01 Emollient Bath Additive Aveeno® Bath oil
    13.02.01.01 Emollient Bath Additive Oilatum® Bath additive
    13.02.01.01 Emollient Bath Additive with Anitmicrobials Dermol®
    13.02.01 Emollient preparation Dermamist®
    06.01.02.03 Empagliflozin Jardiance®
  • Restricted for initiation by diabetes team

    Replaced use of canagliflozin and dapagliflozin
    		•
    13.02.01 Emulsifying Ointment BP  Ointment
    02.05.05.01 Enalapril   Tablet

  • If needed tablets can be crushed and dispersed in water
    		•
    05.03.01 Enfuvirtide Fuzeon®
    02.01.02 Enoximone  Injection 5mg/ml 20ml amp
  • Secondary care use only
  • Plastic apparatus should be used, crystal formation if glass used
    		•
    04.09.01 Entacapone Comtess®
    05.03.03 Entecavir Baraclude® Initiation by specialist consult only
    02.07.02 Ephedrine  Injection (secondary care only)
    12.02.02 Ephedrine  Nasal drops 0.5%
    Nasal drops 1%
    08.01.02 Epirubicin hydrochloride 
    02.02.03 Eplerenone  Cardiology use only

    Tablet 25mg and 50mg
  • Second line agent if spironolactone is not tolerated for use within the licensed indication of stable post MI patients with left ventricular dysfunction and clinical evidence of heart failure in line with NICE guidance.
  • Second line aldosterone antagonist if spironolactone is not tolerated for NYHA class II heart failure.
    • 09.01.03 Epoetin alfa Eprex® Injection

  • Restricted for haematology and renal use only


    		•
    09.01.03 Epoetin beta NeoRecormon® Injection
  • Restricted for haematology and renal use only

    		•
    02.08.01 Epoprostenol 
    02.09 Eptifibatide 
    04.07.04.02 Erenumab 
    • For prophylaxis of migraine
    • For initiation by neurology only as per PAS scheme
    09.06.04 Ergocalciferol 
    07.01.01 Ergometrine Maleate  Injection 500 micrograms/ml
    07.01.01 Ergometrine Maleate and Oxytocin Syntometrine® Injection ergometerine 500 micrograms and oxytocin 5units/ml
    08.01.05 Eribulin Halaven® Available via CDF if the following criteria met

    Treatment of patients with locally advanced or metastatic breast cancer who have been previously treated with (or unsuitable for) an anthracycline, a taxane and capecitabine
    08.01.05 Erlotinib Tarceva®
    08.01.05 Erlotinib Tarceva®
    05.01.02.02 Ertapenem Invanz®
    05.01.05 Erythromycin 
    24.01 Erythromycin  Indication:
    Gastric reflux and Infection
    Dose:
    10 mg/kg qds
    3mg/kg qds for reflux
    Administration
    IV infusion over 60minutes
    Dilute to a conencentration of 5mg in 1ml. Use glucose 5% only.
    Monitoring
    Renal function, LFT,
    Long term use for reflux may cause pyloric stenosis
    Further Info:
    2/52 course for confirmed chlamydia
    Supply:
    Available from pharmacyas named patient. Oral liquid kept as stock.
    04.03.03 Escitalopram  Tablets 5mg, 10mg, 20mg
    Short term management of Generalised Anxiety Disorder
  • Usual dose range 10-20mg
  • Max daily dose 20mg
  • Max single dose 20mg
    		•
    02.04 Esmolol  Injection (secondary care only)
    01.03.05 Esomeprazole 
    10.01.03 Etanercept Enbrel® Subcut injection 25mg and 50mg
  • On recommendation from specialist consultant
    • 13.05.03 Etanercept Benepali

    Benepali is brand of choice at BTFHT, Enbrel should only be prescribed if there has been prior approval from DTC.

    Available as a SC injection - pen/syringes

    Prescribe as per NICE guidelines psoriasis/psoriatic arthritis:

    TA103: Etanercept and efalizumab for the treatment of adults with psoriasis

    TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis

    TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
    05.01.09 Ethambutol  
    24.01 Ethamsylate  Review???
  • For infants < 1500g 12.5 mg/kg/dose qds x 16 doses
  • First dose within 1 hour of birth if possible.
    		•
    07.03.01 Ethinylestradiol / levonorgestrel phased pill TriRegol®, Logynon®, Logynon®ED TriRegol®, Logynon®
  • Phasic standard strength (21 day preparation)

    Logynon®ED
  • Phasic standard strength (28 day preparation)

    Prescribe by brand, TriRegol preferred brand at BTHFT
    		•
    07.03.01 Ethinylestradiol 20 mcg / norethisterone 1mg Loestrin 20® Monophasic standard strength (21 day preparation)
    07.03.01 Ethinylestradiol 20mcg / desogestrel 150mcg Gedarel®, Mercilon® Monophasic low strength (21 day preparation)
  • Prescribe by brand, Gedarel preferred brand at BTHFT
    		•
    07.03.01 Ethinylestradiol 20mcg / gestodene 75 mcg Millinette®20/75, Femodette® Monophasic low strength (21 day preparations)
    07.03.01 Ethinylestradiol 30 mcg / drospirenone 3 mg Yasmin®,Acondro® Monophasic Combined oral contraceptive (21 day preparation)
  • Prescribe by brand, Acondro preferred brand at BTHFT
    		•
    07.03.01 Ethinylestradiol 30mcg / desogestrel 150mcg Gedarel®
    07.03.01 Ethinylestradiol 30mcg / gestodene 75 mcg Millinette®, Femodene®, Femodene®ED Millinette®, Femodene®
  • Monophasic standard strength (21 day preparation)

    Femodene®ED
  • Monophasic standard strength (28 day preparation)

    Prescribe by brand, Millinette preferred brand at BTHFT

    • 07.03.01 Ethinylestradiol 30mcg / levonorgestrel 150mcg Rigevidon®, Microgynon 30® preps, Levest®, Ovranette® Rigevidon®, Microgynon 30®, Levest®, Ovranette®
  • Monophasic standard strength (21 day preparation)

    Microgynon 30 ED®
  • Monophasic standard strength (28 day preparation)

    Prescribe by brand, Levest preferred brand at BTHFT
    		•
    07.03.01 Ethinylestradiol 35 mcg / noresthisterone 500mcg Ovysmen®, Brevinor® Monophasic standard strength (21 day preparation)
    07.03.01 Ethinylestradiol 35 mcg / norgestimate 250 mcg Cilest®
    04.08.01 Ethosuximide 
    15.01.01 Etomidate Etomidate-Lipuro®
    15.01.01 Etomidate Hypnomidate®
    07.03.02.02 Etonorgestrel Nexplanon® Implant (subdermal) 68mg
    08.01.04 Etoposide Etopophos®
    08.01.04 Etoposide 
    10.01.01 Etoricoxib Arcoxia®
    05.03.01 Etravirine Intelence®
    08.01.05 Everolimus Afinitor® Available VIA CDF
    02.12 Evolocumab Repatha®
    • For use in line with NICE TA394
    08.03.04.01 Exemestane 
    10.01.04 Febuxostat 
    02.12 Fenofibrate  Micro Capsule
  • Supralip 160mg is equivalent to 200mg of the other micronised brands.
    • 04.07.02 Fentanyl Actiq® Lozenges 200, 400 and 600 mcicrograms
    04.07.02 Fentanyl  Patch
  • For patients with swallowing difficulties on stable doses of opiates or on pain team specialist advice when morphine isn't suitable.
  • For chronic non-cancer pain, doses greater than 50 micrograms / hour by specialist recommendation or advice only.

    • 15.01.04.03 Fentanyl 
    24.01 Fentanyl  Indication:
    Sedation for intubation
    Dose:
    2 - 3 micrograms/kg/dose
    Administration
    Take 1.0mL (50micrograms) of fentanyl and add to 4.0mL of sodium chloride 0.9%. Giving a concentration of 10micrograms in 1mL.
    Monitoring
    Blood pressure, muscle rigidity and respiratory rate
    Further Info:
    See "Preparation of Drugs for Intubation" document on sharepoint
    Supply:
    Available from pharmacy as a stock item IV as 50micrograms in 1ml - Controlled drug.
    09.01.01.02 Ferric Carboxymaltose Ferinject® One mL of solution contains 50 mg of iron as ferric carboxymaltose

    Determination of the cumulative iron dose
    A single dose of Ferinject should not exceed 1,000 mg of iron (20 mL) per day. Do not administer 1,000 mg of iron (20 mL) more than once a week.

  • Dose Calculation
    Haemoglobin <10g/dL
    Body weight 35 kg to <70 kg = 1500mg
    Body weight > 70kg = 2000mg

    Haemoglobin >10g/dL
    Body weight 35 kg to <70 kg = 1000mg
    Body weight > 70kg = 1500mg

    For patients with a Hb value ≥14 g/dL, an initial dose of 500 mg iron should be given and iron parameters should be checked prior to repeat dosing.

    Note: A cumulative iron dose of 500 mg should not be exceeded for patients with a body weight <35 kg.

    If required oral iron should not be started until at least 5 days post ferrinject dose

    		•
    09.01.01.01 Ferrous Fumarate Fersamal®
    09.01.01.01 Ferrous Gluconate  Tablet 300mg

    300mg tablet = 35mg of iron. Only use if intolerent of other iron salts (but often no better)
    09.01.01.01 Ferrous Sulphate  Tablet 200mg
  • 200mg tablets= 65mg iron
    • 07.04.02 Fesoterodine Toviaz® Tablet 4mg and 8mg
    06.01.01.01 Fiasp® Insulin Aspart
  • Rapid acting recombinant human insulin analogue
  • 10ml vial
  • 3ml cartridge
  • 3ml prefilled pen

  • Restricted for initiation by diabetes team
  • For patients who require more rapid onset of action of insulin than provided by other rapid acting insulins
    		•
    05.01.07 Fidaxomicin Dificlir®
    09.01.06 Filgrastim Zarzio®
    06.04.02 Finasteride  Tablet 5mg
    08.02.04 Fingolimod 
    02.03.02 Flecainide  Tablet, Injection (secondary care only)
    01.06.05 Fleet Phospho-soda®  oral solution
    13.04 Flucinolone Acetonide 0.025% Synalar® Cream, Ointment
  • Potent
    		•
    05.01.01.02 Flucloxacillin 
    24.01 Flucloxacillin  Indication:
    Infection-due to beta-lactamase-producing staphylococci.
    Late onset sepsis guideline
    Dose:
    50mg/kg < 7days BD
    50mg/kg 7-21days TDS
    50mg/kg 21-28days QDS
    Administration
    Dilute reconstituted solution in Glucose 5% or Sodium Chloride 0.9% and give over 30–60 minutes.
    Monitoring
    Renal function, liver function
    Further Info:

    Supply:
    Available from pharmacy as a stock item
    05.02 Fluconazole 
    07.02.02 Fluconazole  Capsule 50 mg and 150mg
  • 150mg STAT dose
  • 50mg daily for 7 days
    		•
    24.01 Fluconazole  Indication:
    Systemic Candida infection
    Dose:
    6 mg/kg/dose
    < 2 weeks old dose each 72hrs
    2-4 weeks old dose each 48hrs
    >4 weeks old dose each 24hrs
    Excreted unchanged in urine so extended dosage interval after first 2 doses if poor renal function.
    Administration
    IV infusion over 30minutes
    Monitoring
    ECG(QT prolongation),renal fucntion, U&E
    Further Info:
    IV contains equivalent of 0.46mmol/kg of sodium for 6mg/kg dose.
    Supply:
    Available from pharmacy as a stock item
    08.01.03 Fludarabine Phosphate Fludara®
    06.03.01 Fludrocortisone Acetate Florinef® Tablet 100 microgram
  • If needed tablets can be dispersed in water. Flush well if giving via enteral tube
    		•
    13.04 Fludroxycortide  Haelan®
    15.01.07 Flumazenil Anexate®
    12.01.01 Flumetasone 0.02% with Clioquinol 1% Locorten-Vioform® Drops
    11.04.01 Fluocinolone intravitreal implant Iluvien®
    • Opthalmology use only
    11.08.02 Fluorescein Sodium Minims® Eye drops 1% and 2%
    11.04.01 Fluorometholone FML® Eye drops 0.1%
    08.01.03 Fluorouracil 
    08.01.03 Fluorouracil 
    11.99.99.99 Fluorouracil  Intravitreal Injection
    Unlicensed - prepared by aseptic unit
    13.08.01 Fluorouracil Efudix®
    04.03.03 Fluoxetine  Capsules 20mg, 60mg (60mg capsules significantly more expensive, prescribe in multiples of 20mg where possible)
    Liquid 20mg/5ml
  • Usual dose range 20-60mg daily
  • Max daily dose 60mg
  • Max single dose 60mg
    		•
    04.02.01 Flupentixol Depixol® Tablet 3mg (depixol)
    Tablets 0.5g and 1mg (fluanxol)
    04.03.04 Flupentixol Fluanxol® Tablets 0.5mg, 1mg
  • Usual dose range 1-3mg
  • Max daily dose 3mg
  • Max single dose 2mg
    		•
    04.02.02 Fluphenazine Decanoate  Depot injection
    04.02.01 Fluphenazine Hydrochloride Moditen® Injection (oily) 25mg/ml and 100mg/ml
    08.03.04.02 Flutamide 
    03.02 Fluticasone Flixotide® Aersol inhaler and Dry powder (Accuhaler)
    03.02 Fluticasone and formoterol Flutiform®

    Aerosol Inhaler

    • 50mcg/5mg, 125mcg/5mcg and 250mcg/5mcg
       
    03.02 Fluticasone and salmeterol Seretide®
  • Evohaler, Accuhaler
    		•
    12.02.01 Fluticasone furoate Avamys® Nasal Spray 27.5 micrograms per spray
    03.02 Fluticasone furoate & vilanterol Revlar Ellipta®
    12.02.01 Fluticasone Propionate  Nasal spray 50micrograms per spray
    12.02.01 Fluticasone Propionate Flixonase Nasule® 0.4ml unit dose vials (400 micrograms/unit dose)
    03.02 Fluticasone with umeclidinium and vilanterol Trelegy Ellipta®

    Trelegy Ellipta 92/55/22 dry powder inhaler
    09.01.02 Folic Acid  Tablet, Syrup

  • Tablets can be crushed and dispersed. Liquid available for paediatrics.
    • 02.08.01 Fondaparinux 
    03.01.01.01 Formoterol  Oxis®
  • Long-acting beta-agonist
  • Only Oxis brand (6mcg and 12mcg) stocked at BTHFT

  • Use Oxis inhaler as alternative to Atimos Modulite, but counsel patient as Oxis is a dry powder inhaler
    • 04.06 Fosaprepitant Ivemend®
    13.05.02 Fumaderm®   Awaiting Service agreement with CCG
    02.02.02 Furosemide  Tablet 20mg and 40mg, Oral Solution 40mg/5ml, Injection 10mg/ml
    24.01 Furosemide  Indication:
    Chronic lung disease, renal failure and as a diuretic
    Dose:
    1mg/kg/dose bd, See neonatal formulary
    Administration
    IV or oral over 4-5 minutes not exceeding a rate of 500 micrograms/kg/minute
    Monitoring
    U&E, Ca, Blood sugars, urine output
    Nephrocalcinosis and nephrolithiasis reported with long-term use of furosemide in preterm infants
    Further Info:
    IV formulation can be given orally after dilution with sterile water if necessary.
    Supply:
    Available from pharmacy as an oral liquid (40mg in 5ml)
    11.03.01 Fusidic Acid  Eye drops 1%
  • Alternative to chloramphenicol for empirical treatment in people who:
    - Are pregnant.
    - Have a personal or family history of blood dyscrasias, such as aplastic anaemia.
    - Are intolerant of chloramphenicol.
    - Need a twice-a-day treatment for infective conjunctivitis
    		•
    13.10.01.02 Fusidic Acid 2%  Cream and Ointment
  • High level of resistance in general population due to over use
    		•
    04.07.03 Gabapentin  Capsule (100mg, 300mg and 400mg strengths)
    04.08.01 Gabapentin 
    04.11 Galantamine Reminyl® Tablets 8mg, 16mg XL and 24mg XL, Oral liquid 4mg/ml

    Second Line for Mild to moderate Alzheimers disease
  • Usual dose range 16-24mg
  • Max daily dose 24mg XL
  • Max sinlge dose 24mg XL
    		•
    05.03.02.02 Ganciclovir Cymevene®
    11.03.03 Ganciclovir 0.15% ophthalmic gel Virgan®
    01.01.02 Gaviscon   suspension, 3.1mmol sodium per 5ml
    01.01.02 Gaviscon Advance  suspension, contains 2.3mmol sodium and 1mmol potassium per 5ml.
    01.01.02 Gaviscon Infant  Oral powder, contains 0.92mmol sodium per dose
    NOTE: each half dual sachet is identified as one dose. To avoid errors prescribe in terms of 'dose'
    08.01.05 Gefitinib Iressa® Available via a patient access scheme, please register patients when initiating treatment
    09.02.02.02 Gelatin Gelofusine® Infusion
  • 500ml and 1 litre bags available
    • 09.02.02.02 Gelatin Haemaccel®
    12.03.01 Gelclair®  Oral gel - sachets
    08.01.03 Gemcitabine Gemzar®
    07.01.01 Gemeprost  Pessaries 1mg
  • currently not available
    		•
    05.01.04 Gentamicin 
    11.03.01 Gentamicin ophthalmic Available as:
    - Eye drops 0.3%
    - Eye drops 0.3% (preservative free - unlicensed)

    Specialist use only
    12.01.01 Gentamicin Genticin® Drops 0.3%
    24.01 Gentamicin  Indication:
    Infection
    Dose:
    4 mg/kg IV slow bolus
    >= 28/40 once daily
    <28/40 36hourly
    Administration
    IV injection over 3-5 minutes or infusion over 30 minutes
    Monitoring
    Levels before 3rd dose >=28/40
    Levels before 2nd dose <28/40
    Pre dose levels only (trough).
    Levels >2mg/L are considered undesirable, consider modifying dose interval if treatment is to be continued
    Levels are not necessary if it is likely gentamicin will be stopped at third dose for negative blood cultures.
    It is appropriate to stop blood cultures 36 hours or so after they have been taken, as opposed to when they were recorded as arriving in the lab, if baby was always well.
    Further Info:
    Gentamicin should be prescribed at 0600, 1200, 1800, 2400 times when being administered on postnatal wards, to minimise risk of maladministration.
    Supply:
    Available from pharmacy as a stock item. Ensure ONLY the 20mg in 2ml vial is used
    06.01.02.01 Gliclazide  Tablet 40mg and 80mg
  • Only 80mg tablets stocked at BTHFT
  • If needed tablets can be crushed and dispersed in water. Liquid can be made specially if required.
    • 06.01.02.01 Gliclazide MR  MR tablet 30mg
  • Gliclazide mr/r 30mg approximately equivalent in therapeutic effect to standard formulation gliclazide 80mg
    		•
    06.01.02.01 Glimepiride  Tablets 1mg, 2mg, 3mg and 4mg
    06.01.04 Glucagon GlucaGen® HypoKit 1 unit of glucagon = 1mg of glucagon
    06.01.04 GlucoGel® 
    09.02.02.01 Glucose Intravenous  Available in multiple strengths

    Infusion
  • Dextrose 5% infusion 50ml, 100ml, 250ml, 500ml, 1 litre
  • Dextrose 10% infusion 500ml
  • Dextrose 20% infusion 100ml,500ml
  • Dextrose 50% infusion 500ml

    Ampoules
  • Dextrose 10% 10ml ampoules
  • dextrose 50% 50ml ampoules
    		•
    13.07 Glutaraldehyde Glutarol®
    01.06.02 Glycerol (Glycerin)  Suppository, available in 1g (infant), 2g (child) and 4g (adult)
    02.06.01 Glyceryl Trinitrate  Available as Tablet (S/L & Buccal), Spray, Patches, Injection.

    Injection restricted (secondary care only)- Use Polyethylene (PE), giving set for infusion (NOT PVC!).
    01.07.04 Glyceryl Trinitrate 0.4% Rectogesic® Ointment
    07.04.04 Glycine 
    09.08.01 Glycine  
    • Capsules
    • Use by specialist metabolic service only
    03.01.02 Glycopyrronium Seebri breezhaler® Inhalation capsule (50micrograms/dose)
  • for use with Seebri Bteezhaler
    		•
    15.01.03 Glycopyrronium 
    01.05.03 Golimumab Simponi ®

    To be used as per NICE guidelines:

    TA329: Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy
    10.01.03 Golimumab Simponi®
    13.05.03 Golimumab Simponi

    As per NICE guidelines

    TA220: Golimumab for the treatment of psoriatic arthritis
    06.05.01 Gonadorelin HRF®
    06.07.02 Goserelin  Subcut injection (implant) 3.6mg and 10.8mg
    08.03.04.02 Goserelin Zoladex®
    08.03.04.02 Goserelin Zoladex® LA
    08.03.04.01 Goserelin-Zoladex® 
    05.02 Griseofulvin 
    13.05.03 Guselkumab Tremfya

    To be prescribed as per NICE guidelines for plaque psoriasis:

    TA521: Guselkumab for treating moderate to severe plaque psoriasis
    09.08.02 Haem Arginate Normasang®
    14.04 Haemophilus influenzae type B Combined Vaccine Menitorix®
    04.02.01 Haloperidol  Tablets 0.5mg, 1.5mg, 5mg, 10mg
    Oral solution 10mg/5ml
    First generation anitpsychotic
    Management of acutely disturbed behaviour
  • Usual ORAL dose range 1.5mg-5mg upto two to three times daily
  • Max daily dose 30mg
  • Max single dose 10mg
    		•
    04.02.01 Haloperidol  Injection 5mg/ml (intramuscular)
    Management of acutely disturbed behaviour
  • Usual dose range 2-10mg, then every 4-8hours according to response, Elderly initially half adult dose
  • Max daily dose 12mg (reduced according BNF June 2014)
  • Max single dose 2-10mg
    		•
    04.02.02 Haloperidol Haldol Decanoate® Injection (oily) 50mg/ml and 100mg/ml
    02.08.01 Heparin  Heparin sodium 10 units/ml (for IV line flushes only)

    02.08.01 Heparin  Heparin sodium 1000 units/1mL.
    14.04 Hepatitis A vaccine 
    14.04 Hepatitis A vaccine Single Component Avaxim®
    14.04 Hepatitis A vaccine Single Component Vaqta® Paediatric
    14.04 Hepatitis A vaccine with Hepatitis B vaccine  Twinrix®
    14.05.02 Hepatitis B immunoglobulin  Obtain direct from LGI Virology Mon-Fri: 08.30-17:00 Tel: 0113-3928750/49 or 3928665

    Out of Hours: Seacroft Lodge: 0113-2063283 (ask for Consultant Virologist)
    14.04 Hepatitis B vaccine 
    14.04 Hepatitis B vaccine Single Component Engerix B®
    14.04 Hepatitis B vaccine Single Component HBvaxPRO®
    06.01.01.01 Humalog® Insulin Lispro
  • Rapid acting recombiant human insulin analogue
  • 10mL vial
  • 3mL cartridge for Autopen® Classic or HumaPen®
  • 3mL prefilled Humalog® KwikPen
    		•
    06.01.01.01 Humulin R® Insulin 500 units in 1mL
  • Insulin 500 units in 1mL
  • 20 ml vial (high strength)

    For use by specialist diabetic consultants
    • 06.01.01.01 Humulin S® Soluble insulin
  • Short acting human soluble insulin
  • 10mL vial
  • 3mL cartridge (for most Autopen® Classic or HumaPen®)
    • 06.01.01.02 Humulin® I Isophane Insulin
  • Intermediate/long acting human isophane insulin
  • 10mL vial
  • 3mL cartridge
  • 3mL prefilled KwikPen
    • 10.01 Hyaluronic acid Hyalgan®
    10.03.01 Hyaluronidase Hyalase®
    02.05.01 Hydralazine  Tablet 25mg, 50mg, Suspension 5mg/5ml
    01.05.02 Hydrocortisone Colifoam®
    06.03.02 Hydrocortisone  Tablets 10mg and 20mg, Injection 100/ml
  • if needed tablets can be dispersed in water
    		•
    12.03.01 Hydrocortisone Corlan® Pellets 2.5mg
    13.04 Hydrocortisone  Cream (0.5% and 1%), Ointment (0.5% and 1%)
  • Mild
    		•
    13.04 Hydrocortisone Hydromol® HC Intensive
    13.04 Hydrocortisone 1% with Clotrimazole 1% Canesten HC® Cream
  • Mild with antifungal
    • 13.04 Hydrocortisone 1% with Miconazole Nitrate 2% Daktacort® Cream, Ointment
  • cream stored in the fridge, ointment room temperature
    Mild with antifungal
    • 13.04 Hydrocortisone 1%, Clioquinol 3% Vioform-Hydrocortisone®
    13.04 Hydrocortisone 1%, Urea 10% and Lactic Acid 5% Calmurid HC®
    10.01.02.02 Hydrocortisone acetate Hydrocortistab® Injection 25mg/ml
    13.04 Hydrocortisone Acetate 1% with Fusidic Acid 2% Fucidin H® Cream
  • Mild with antimicrobial
    • 12.01.01 Hydrocortisone Acetate 1% with Gentamicin 0.3% Gentisone® HC Drops
    13.04 Hydrocortisone Butyrate Locoid®
    13.11.06 Hydrogen Peroxide Crystacide®
    13.11.06 Hydrogen Peroxide Solution BP 
    13.02.01 Hydromol®  Cream, Ointment
    13.02.01.01 Hydromol® bath and shower 
    04.07.02 Hydromorphone Palladone® Capsules m/r
    09.01.02 Hydroxocobalamin  IM Injection
  • vitamin B12 of choice for therapy - retained in the body longer

    		•
    08.01.05 Hydroxycarbamide 
    08.01.05 Hydroxycarbamide Hydrea®
    09.01.03 Hydroxycarbamide 
    10.01.03 Hydroxychloroquine  Tablet 200mg

    Tablets may be crushed and dispersed in water, liquid (unlicensed special) can be made specially if required.
    13.05.03 Hydroxychloroquine 

    Oral medication

    SWYAPC shared care guidelines
    11.08.01 Hydroxypropyl Guar Systane® Eye drops
    03.04.01 Hydroxyzine  Tablets 10mg and 25mg, Liquid 10mg/5ml
  • Drowsy antihistamine, longer duration of action than chlorphenamine
    		•
    01.02 Hyoscine Butylbromide Buscopan® Tablets 10mg, Injection 20mg/ml
    04.06 Hyoscine Hydrobromide 
    15.01.03 Hyoscine Hydrobromide 
    11.08.01 Hypromellose 

    Eye drops 0.3%
    11.08.01 Hypromellose Isopto Alkaline® Eye drops 1%
    11.08.01 Hypromellose Isopto Plain® Eye drops 0.5%
    11.08.01 Hypromellose Optive Fusion Eye drops
  • For the treatment of severe dry eyes
  • Only for use by opthalmic department
  • Replaces use of Optive eye drops
    		•
    11.08.01 Hypromellose 0.3% with Dextran 70 0.1% Tears naturale® Eye drops
    06.01.01.02 Hypurin® Bovine Isophane Isophane Insulin
  • Intermediate acting bovine insulin
  • 10mL vial
  • 3mL cartridge (fits AutoPen Classic)
    • 06.01.01.01 Hypurin® Bovine Neutral Soluble insulin
  • Short acting bovine (highly purified) soluble insulin
  • 10ml vial
  • 3ml cartidges for Autopen® Classic
    		•
    06.01.01.01 Hypurin® Porcine Neutral Soluble insulin
  • Short acting porcine (highly purified) soluble insulin
  • 10ml vial
  • 3ml cartridge for Autopen® classic
    		•
    06.01.01.02 Hypurin®Bovine Lente Insulin Zinc suspension
  • Long acting bovine insulin
  • 10mL vial
    • 06.06.02 Ibandronic Acid Bondronat® Tablet 50mg, Infusion 1mg/ml
    06.06.02 Ibandronic Acid Bonviva® Tablets 150mg, Injection 1mg/ml
  • Tablet 150mg once MONTHLY dose
    		•
    08.01.05 Ibrutinib  Imbruvica®
  • For use in line with NICE TA429

  • Complete full hepatitis B serology including hepatitis B core antibody status before initiation. If this is positive please refer to Dr Moreea/Dr Southern for advice (see MHRA Drug Safety Update below)
    		•
    10.01.01 Ibuprofen 
    • Tablet 200mg and 400mg, suspension (100mg/5ml)
       
    24.01 Ibuprofen  Indication:
    Patent Ductus Arteriosus
    Dose:
    10 mg/kg loading dose then,
    5 mg/kg OD for 2 days
    Administration
    slow IV bolus or infuse over 15mins
    Oral can be considered if IV access is an issue.
    Monitoring
    Renal function, liver function, platlets and bilirubin
    Further Info:
    May be diluted in sodium chloride 0.9% or glucose 5% if necessary.
    Avoid steroids during course if possible.
    Supply:
    Available from pharmacy as a stock item.
    Double check strength! TWO strengths currently stocked due to manufacturer supply issues.
    08.01.02 Idarubicin Hydrochloride Zavedos®
    09.08.01 Idursulfase Elaprase®
    08.01.01 Ifosfamide Mitoxana®
    02.05.01 Iloprost injection   Injection
    Restricted for vascular use
    08.01.05 Imatinib Gilvec®
    24.01 Imipenem  Indication:
    Infection-
    Dose:
    20 mg/kg dose
    < 7days BD
    7 - 21 days TDS
    21 - 28 days QDS
    Dose frequency should be reduced if renal failure suspected and stopped if patient anuric.
    Caution in CNS disorders
    Administration
    IV infusion over at least 30minutes
    Dilute to a concentration of 5mg/ml(imipenem) in sodium chloride 0.9% or glucose 5%.
    Monitoring
    Renal function, hypotension, seizures, myoclonic activity,thrombocytopenia, neurotoxicity(see neonatal formulary)
    Further Info:
    Also refered to as Imipenem with cilastatin.
    Prescribe in terms of Imipenem
    Supply:
    Available from pharmacy as a named patient.DSU cannot manufacturer.
    04.03.01 Imipramine  Tablets 10mg, 25mg
  • Usual dose range 75-200mg in divided doses
  • Max daily dose 200mg (300mg in hospital)
  • Max single dose 150mg
    		•
    13.07 Imiquimod Aldara®
    24.01 Immunisations  See BNF-C share point document
    14.04 Inactivated Influenza Vaccine (Split Virion) 
    03.01.01.01 Indacaterol  Inhalation pwder, hard capsule with device
  • 150 and 300 microgrammes per inhalation
  • Specialist initiation
    		•
    02.02.01 Indapamide  Tablet 2.5mg, M/R tablets 1.5mg

  • If needed standard tablets can be dispersed in water for patients with swallowing difficulties or enteral tubes terminating in the stomach. MR tablets should not be crushed.
    • 05.03.01 Indinavir Crixivan®
    10.01.01 Indometacin  Tablets 25mg, 50mg
    24.01 Indomethacin  IV NOT available, REVIEW??

    Either:
    200mcg/kg IV then 100mcg/kg daily for 5 days
    or
    200mcg/kg repeated 12hourly x 3 doses in total
    Watch for renal and GI side effects.
    Make 100microgram / ml solution by diluting 1mg in 10ml 0.9% saline, use infusion pump to infuse appropriate dose over 20mins.
    01.05.03 Infliximab Remsima

    Remsima is the brand of choice at BTHFT, Remicade can only be prescribed if approved by DTC.

    Remsima is now available as an IV infusion and SC injection. For more information about dosing, contact the pharmacy or gastroenterology teams.

    To be used as per NICE guidelines:

    TA163: Infliximab for acute exacerbations of ulcerative colitis

    TA187: Infliximab and adalimumab for the treatment of Crohn's disease

    TA329: Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy
    10.01.03 Infliximab Remicade®
    13.05.03 Infliximab Remsima

    Remsima is brand of choice at BTHFT. Remicade should only be prescribed if approved by DTC.

    Remsima is now available as an infusion and SC formulation.

    To be prescribed as per NICE guidelines for psoriasis/psoriatic arthritis:

    TA134: Infliximab for the treatment of adults with psoriasis

    TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis

     
    14.04 Influenza vaccine  
    24.01 Insulin Actrapid Indication:
    Hyperglycaemia
    Dose:
    Dose range 0.02-0.1units/kg/hour
    Start at 0.05 units/kg/hour
    For hyperkalaemia 1 unit is needed for every 30g of glucose.
    Administration
    IV infusion
    5 units of soluble insulin(Actrapid) into 50mls 5%dextrose(0.1units/ml)
    See “Insulin – making up and giving” guideline
    Monitoring
    Blood sugars, potassium, glucosuria and blood gases.
    Further Info:
    Prime lines and slowly flush with 10mls of infusion to prevent insulin binding to plastic.
    Insulin is generally given by a separate intravenous cannula, but when circumstances prevent this an insulin infusion may be connected aseptically to the ’lipid port’.
    Supply:
    Available from pharmacy as a stock vial. DSU cannot make due to product expiry.
    06.01.01.02 Insuman® Basal Isophane Insulin
  • Intermediate acting human isophane insulin
  • 5ml vial
  • 3ml cartridge
  • 3ml SoloStar® prefilled pen
    		•
    06.01.01.01 Insuman® Rapid Soluble insulin
  • Short acting human soluble insulin
  • 3mL cartridge for ClikSTAR® and Autopen®
    		•
    08.02.04 Interferon Alfa 
    08.02.04 Interferon Alfa Roferon-A®
    08.02.04 Interferon Alfa Viraferon® Initiated by hepatitis specialist team
    07.03.04 Intra-uterine Contraceptive Devices Load® 375
    07.03.04 Intra-uterine Contraceptive Devices Nova-T® 380
    07.03.02.03 Intra-uterine Progestogen Only System Mirena® Intra-uterine device
  • Releases Levonorgesterol 20 micrograms/24hours
    		•
    06.02.02 Iodine and Iodide  Aqueous oral solution, total iodine 130mg/ml
  • Also known as Lugol's iodine

    		•
    03.01.02 Ipratropium 
  • Inhaler CFC-free (20micrograms/dose), Nebuliser solution (250 and 500 micrograms/ml).
    		•
    12.02.02 Ipratropium Bromide Rinatec® Nasal spray 0.03%, ipratropium bromide 21 micrograms/metered spray
    02.05.05.02 Irbesartan  Tablets
  • If needed tablets can be crushed and dispersed in water. Drug is poorly soluble
    		•
    08.01.05 Irinotecan Hydrochloride Campto®
    09.01.01.02 Iron Dextran CosmoFer® Ferinject first line
  • Only use if contraindicated to ferinject
    		•
    09.01.01.02 Iron Sucrose Venofer® Ferinject first line
  • Venofer is used first line for haemodialysis patients as they are having 100mg doses regularly, hence more cost effective for this indication
    • 05.02.01 Isavuconazole 
    • For use by infectious diseases and microbiology team only
    15.01.02 Isoflurane 
    05.01.09 Isoniazid 
    06.01.01.02 Isophane Insulin Hypurin® Porcine Isophane
    06.01.01.02 Isophane Insulin Insulatard® 10mL vial
    3mL cartridge
    InnoLet
    02.07.01 Isoprenaline  Infusion (secondary care only)

    02.06.01 Isosorbide Dinitrate  Short acting tablet, spray

    Injection- 25mg/50ml ampoule (secondary care only)
  • Use prepared solution of Isoket 0.05% (25mg/50ml ampoule). Administer by syringe pump. Start at 4ml/hour (2mg/hr). Increase the rate to a maximum of 20ml/hr (10mg/hr) if symptoms persist. decrease the rate if the systolic BP fall below 90mmHG
  • For additional advice speak to CCU
    		•
    02.06.01 Isosorbide Mononitrate  Tablet, MR tablet
  • Short acting preparations should be prescribed asymmetrically to reduce the risk of nitrate tolerance
  • If needed tablets can be crushed and dispersed in water. Do not crush MR tablets.
  • MR is aonce daily, long acting preparation
    		•
    13.06.01 Isotretinoin Isotrex® gel
    13.06.02 Isotretinoin Roaccutane® Specialist dermatology prescribers only
    01.06.01 Ispaghula Husk  Granules
    05.02 Itraconazole Sporanox®
    02.06.03 Ivabradine  Tablet 7.5mg and 15mg
    13.06 Ivermectin  Soolantra®
  • Cream
  • Topical treatment of inflammatory lesions of rosacea (papulopustular) in adult patients
    		•
    13.10.04 Ivermectin 
    13.05.03 Ixekizumab Taltz®

    To be prescribed as per NICE guidelines:

    TA442: Ixekizumab for treating moderate to severe plaque psoriasis

    TA537: Ixekizumab for treating active psoriatic arthritis after inadequate response to DMARDs

     
    15.01.01 Ketamine injection Ketalar®
    13.09 Ketoconazole  Shampoo
    13.10.02 Ketoconazole 
    11.08.02 Ketorolac Acular® Eye drops 0.5%
    15.01.04.02 Ketorolac Toradol®
    11.04.02 Ketotifen Ketofall®
    • Preservative free eye drop
    01.06.05 Klean-Prep®  Oral powder
    02.04 Labetalol  Tablet, (Injection - secondary care only)
  • If needed tablets can be crushed and dispersed in water. Administer immediately as drug is sensitive to oxidation.
    • 04.08.01 Lacosamide  Vimpat ®
    07.02.02 Lactic acid Balance Activ Rx® Vaginal gel
    01.06.04 Lactulose  Solution
    05.03.01 Lamivudine Zeffix®
    04.02.03 Lamotrigine  Tablets 25mg, 50mg, 100mg, 200mg ; dispersible tablets also available
  • Usual dose range 50-200mg daily with valproate
  • 100mg-400mg daily without valproate
    		•
    04.08.01 Lamotrigine 
    08.03.04.03 Lanreotide Somatuline Autogel®
    08.03.04.03 Lanreotide Somatuline® LA
    01.03.05 Lansoprazole 
  • Capsules first line, 15mg and 30mg
  • Capsules can be opened and beads swallowed without crushing, or can be mixed with food or drink

  • Restricted Item orodispersible tablets restricted for use in patients with swallowing difficulties or who are on enteral tube feeding. They are also licensed to be given via a NG tube or oral syringe if diluted in 5-10ml water


    		•
    09.05.02.02 Lanthanum Fosrenol ® Tablet
    06.01.01.02 Lantus® Insulin Glargine
  • Intermediate/long acting recombinant human insulin analogue
  • 10mL vial
  • 3mL cartridge for ClikSTAR
  • 3mL disposable prefilled pen - Solostar®
    • 08.01.05 Lapatinib Tyverb® Lapatinib with capecitabine - VIA CDF - for locally reccurent or metastatic breast cancer
    09.08.01 Laronidase Aldurazyme®
    11.06 Latanoprost  Eye drops 0.005%
    11.06 Latanoprost Monopost® Eye drops 0.005% Preservative free
  • Single dose 30x0.2ml
  • Only for use in ophthalmics as a second line agent to standard latanoprost (preserved) where the patient has developed an allergy/intolerance to the preservative. Please also note that Saflutan (Tafluprost) (single dose/preserbvative free) will cease to be used.


    		•
    11.06 Latanoprost 0.005% with timolol 0.5% Fixapost®

     

    • Preservative free 0.2ml unit dose eye drop
    • Opthalmology only
    • To be used if patient reacts to preservative containing drops (latanoprost/timolol)
    11.06 Latanoprost 0.005% with Timolol 0.5% Xalacom® Eye drops
    10.01.03 Leflunomide 
    08.02.04 Lenalidomide 
    08.03.04.01 Letrozole 
    08.03.04.02 Leuprorelin Acetate Prostap® SR
    08.03.04.02 Leuprorelin Acetate Prostap® 3
    06.01.01.02 Levemir® Insulin Detemir
  • Long acting recombinant human insulin analogue
  • 3mL cartridge for NovoPen® devices
  • 3mL prefilled FlexPen®
    		•
    04.08.01 Levetiracetam 
    11.06 Levobunolol  Eye drops 0.5%
    15.02 Levobupivacaine Chirocaine®
    04.09.01 Levodopa 
    05.01.12 Levofloxacin 
    11.03.01 Levofloxacin 
    04.02.01 Levomepromazine Nozinan®
    07.03.05 Levonogrestrel Levonelle® 1500 Tablet 1.5mg
  • Single dose as soon as possible after coitus preferbaly within 12 hours but no later than after 72 hours (3 days. May be used between 72 and 96 hours but efficacy decreases with time.
    • 06.02.01 Levothyroxine  Tablets 25mcg, 50mcg,100mcg
    Liquid 25mcg/5ml, 50mcg/ml, 100mcg/5ml - significantly more expensive than tablets, only use where necessary
  • If needed tablets can be crushed and dispersed in water
    		•
    02.03.02 Lidocaine  Injection, Minijet(disposable syringe)
    15.02 Lidocaine  Versatis® Medicated plasters 5%

  • Restricted for pain management service recommendation only
  • Apply for 12 hours followed by a 12 hour plaster-free period
  • Discontinue if no repsonse after 4 weeks
    		•
    15.02 Lidocaine 2.5% with Prilocaine 2.5% EMLA®
    15.02 Lidocaine2% with Chlorhexidine 0.25% Instillagel®
    15.02 Lignocaine 
    01.06.07 Linaclotide Constella®
    06.01.02.03 Linagliptin Trajenta® Tablet 5mg
  • First choice DPP4 inhibitor at BTHFT
    		•
    05.01.07 Linezolid 
    06.02.01 Liothyronine  Available as tablets or injection

  • Tablets. For specialist initiation. Discuss with endocrinologist before initiation. Similar action to levothyroxine but is ore rapidly metabolised and has more rapid effect. 20-25 microgrames is equivalent to 100 micrograms of levothyroxine
  • Injection also known as triiodothyronine

    • 11.08.01 Liquid Paraffin Lacri-Lube®

    Eye ointment

    • Prescribe Xailin night (same formulation more cost effective)
    11.08.01 Liquid Paraffin Xailin Night®

    Eye ointment
    06.01.02.03 Liraglutide Victoza® injection 6mg/ml
    02.05.05.01 Lisinopril  Tablets, Oral solution
  • If needed tablets can be dispersed in water

    Restricted Item Oral solution, for genuine swallowing difficulties or NG tubes
    		•
    04.02.03 Lithium Carbonate Camcolit® Tablets 250mg (Li 6.8 mmol), 400mg (Li 10.8mmol)
  • Prescribe by brand
  • Usual dose range 400-1200mg daily
  • Max daily dose is adjustable
    • 04.02.03 Lithium Carbonate Priadel® Tablets 250mg(Li 5.4mmol), 400mg (Li 10.8mmol)
    Prescribe by brand
  • Usual dose range 400-1200mg daily
  • Max daily dose is adjustable
    • 04.02.03 Lithium Citrate Li-Liquid®
    04.02.03 Lithium Citrate Priadel® Liquid (priadel) 520mg/5ml (Li 5.4mmol/5ml)
  • Prescribe by brand
  • Usual dose range 400-1200mg daily ; 5mls = 200mg lithium carbonate
    		•
    11.04.02 Lodoxamide Alomide® Eye drops 0.1%
    04.03.01 Lofepramine  Tablets 70mg
    08.01.01 Lomustine 
    01.04.02 Loperamide  Capsule 2mg, Tablets 2mg, Syrup (1mg/5ml)
    03.04.01 Loratadine  Liquid 5mg/5ml
  • Tablets not stocked, use desloratidine
    		•
    04.01.02 Lorazepam  Tablet 1mg, 2.5mg
  • Usual dose range: 1 to 4mgdaily in divided doses
  • Max daily dose 4mg
  • Max single dose 2mg
    		•
    04.01.02 Lorazepam injection injection 4mg/ml
  • Usual dose range: 1 to 4mg daily in divided doses
  • Max daily dose 4mg
    		•
    15.01.04.01 Lorazepam 
    02.05.05.02 Losartan  Tablets
  • 1st line choice ARB if patients haven't tolerated an ACE inhibitor

  • Licensed for Renal protection in type 2 diabetic patients with nephropathy (macroalbuminuria) (unlike candesartan)

  • If needed tablets can be crushed and dispersed in water
    		•
    11.04.01 Loteprednol Lotemax® Eye drops 0.5%
    01.06.07 Lubiprostone Amitiza® Capsules 24micrograms

  • Only to be prescribed by Gastro/Colorectal consultants
  • Treatment of chronic idiopathic constipation as per NICE criteria
  • Adult over 18 years, 24 micrograms twice daily for 2 weeks

    		•
    13.06.02 Lymecycline Tetralysal®300 Capsules 408mg
    01.06.04 Macrogol Movicol® Sachets
    01.06.04 Macrogol Movicol®- Half Sachets
    09.05.01.03 Magnesium Glycerophosphate  Tablet (unlicensed)
  • Contains 4mmol magnesium per tablet
  • Tablets can be crushed and dispersed in water.
    • 09.05.01.03 Magnesium Sulphate 
    24.01 Magnesium Sulphate  Indication:
    Hypomagnesemia, PPHN
    Dose:
    For low magnesium (usually <0.5mmol/l) 100mg/kg bd IM or oral usually x 2 doses
    For PPHN loading dose 250mg/kg over 10 mins then 20-75 mg/kg/hour IV infusion
    Administration
    4ml of magnesium sulphate 50%(2g or 8.2mmol) made up to 40 mls with glucose 10%.(50mg/ml)
    Monitoring
    High doses often produce hypotonia, respiratory depression, systemic as well as pulmonary vasodilation.
    Further Info:

    Supply:
    Available from pharmacy as ward stock. Magnesium Sulphate 50% comes as a 2ml or 10ml ampoule
    13.10.05 Magnesium Sulphate Paste BP 
    01.01.01 Magnesium Trisilicate Mixture BP  Suspension, 6mmol sodium/10ml
    01.06.04 Magrogol Movicol® Paediatric Sachets
    02.02.05 Mannitol  IV infusion
    05.03.01 Maraviroc 
    14.04 Measles, Mumps and Rubella Vaccine, Live (MMR) 
    01.02 Mebeverine Hydrochloride  135mg Tablet
  • 200mg MR Tablet non-formulary
  • Oral suspension also available (50mg/5ml) but significantly more expensive
    		•
    01.02 Mebeverine Hydrochloride Colofac® MR Use mebeverine 135mg tablets
    06.04.01.02 Medroxyprogesterone Acetate  Tablet 5mg and 10mg
    07.03.02.02 Medroxyprogesterone Acetate Depo-Provera® Injection 150mg/ml
    08.03.02 Medroxyprogesterone Acetate Provera®
    10.01.01 Mefenamic Acid  Capsules 250mg, Tablets 500mg
    08.03.02 Megestrol Acetate Megace®
    04.01.01 Melatonin 
    08.01.01 Melphalan 
    04.11 Memantine Ebixa® Tablets 10mg and 20mg
    First Line for Moderate to Severe Alzheimers disease
  • Usual dose range 10-20mg
  • Max daily dose 20mg
  • Max single dose 20mg
    		•
    09.06.06 Menadiol Sodium Phosphate 
    14.04 Meningococcal group C conjugate vaccine 
    15.02 Mepivacaine Scandonest Plain®
    03.04.02 Mepolizumab Nucala®
  • Initiation by specialist respiratory consultant for severe refractory eosinophilic asthma in adults only
    		•
    04.07.02 Meptazinol Meptid®
    09.08.01 Mercaptamine Cystagon®
    01.05.03 Mercaptopurine  Tablets 50mg
    08.01.03 Mercaptopurine 
    05.01.02.02 Meropenem 
    24.01 Meropenem  Indication:
    Infection
    Dose:
    <7days 40mg/kg 12 hourly
    >7days 40mg/kg 8 hourly
    >1 month 40mg/kg 8 hourly
    If renal failure of any severity is suspected, reduce dose and interval, see below:
    Mild (eGFR 26-50ml/min) 20mg/kg 12hourly
    Moderate (eGFR 10-25ml/min) 10mg/kg 12hourly
    Severe (eGFR <10ml/min) 10mg/kg 24houly
    Administration
    Dilute to 10mg/ml (using displacemnt values) in glucose 5% or sodium chloride 0.9%.
    IV infusion over 15-30minutes
    Monitoring
    Review renal function before prescribing and review daily:
    Further Info:

    Supply:
    Available from pharmacy as stock. DSU can supply named patient syringes.
    01.05.01 Mesalazine Octasa®
    • Tablets 400mg and 800mg
       
    01.05.01 Mesalazine  Mezavant® XL Tablets m/r, 1.2g
  • Once daily dosing
    		•
    01.05.01 Mesalazine Pentasa®

    Available as:

    • 500mg, 1g modified-release tablets
    • 1g, 2g, 4g modified-release granules sachets 
    • 1g rectal suppositories
    • 1g/100ml enema 
    01.05.01 Mesalazine Salofalk® Granules 500mg, Enema 2g
  • Salofalk tablets not stocked at BTHFT, use Octasa or Pentasa
    		•
    08.01 Mesna 
    02.07.02 Metaraminol  Injection (secondary care only)
    06.01.02.02 Metformin  Tablet 500mg, 850mg, Tablet MR 500mg, 750mg, 1000mg (for patients with proven GI intolerance), Oral powder 500mg, 1000mg
  • If needed tablets may be crushed and dispersed in water or a powder formulation is now available.
    		•
    04.07.02 Methadone  Tablet, Liquid
  • For initiation by pain team only when used as an analgesic

    • 04.10.03 Methadone  Liquid 1mg/ml sugar free
    Substance misuse
  • Usual dose range 30-120mg

    Always confirm with patients substance misuse service or regular community pharmacy to confirm the dose before prescribing. Contact details for Bradford Substance Misuse:

    Bradford Substance Misuse Directory

    		•
    01.05.03 Methotrexate  Tablets 2.5mg

  • 2.5mg tablets preferred

  • Cytotoxic, DO NOT crush and disperse in water

    		•
    08.01.03 Methotrexate 
    10.01.03 Methotrexate 
    10.01.03 Methotrexate Metoject®
    13.05.03 Methotrexate 

    Oral medication - prescibed as 2.5mg tablets

    Methotrexate once-weekly for autoimmune diseases: new measures to reduce risk of fatal overdose due to inadvertent daily instead of weekly dosing

    SWYAPC shared care guidelines
    02.05.02 Methyldopa  Tablet
  • Should only be used for hypertension when other agents have failed or aren't suitable.
  • If needed tablets can be crushed and dispersed in water. Crush thoroughly and flush tube well to prevent blockage.
    • 01.06.06 Methylnaltrexone Relistor® Vials

    Restricted for management of intractable opioid induced constipation in patients not responding to usual laxative treatment - Palliative care teams only
    04.04 Methylphenidate  Tablets
    Drug treatment of attention deficit hyperactivity disorder (ADHD)
  • Concerta XL
    Usual dose range 18mg - 54mg
    Max daily dose 108mg

  • Equasym XL
    usual dose range 10mg-60mg
    Max daily dose 90mg (unlicensed)

  • Medikinet XL
    Usual dose range 10mg-60mg
    Max daily dose 90mg (unlicensed)

    		•
    06.03.02 Methylprednisolone  Tablets 2mg, 4mg 16mg and 100mg
    Injection (solu-medrone) 40mg, 125mg, 500mg and 1g vial
    Intramuscular depot 40mg/ml
    10.01.02.02 Methylprednisolone Acetate Depo-Medrone® Injection 40mg in 1mL
    Injection 80mg in 2mL
    04.06 Metoclopramide  Tablet, Liquid, Injection
  • Not recommended for patients under 20 years of age due to risk of dystonic reactions
  • Metoclopramide should only be prescribed for short-term use (up to 5 days).
  • For adults, the maximum dose in 24 hours is 30 mg (or 0.5 mg per kg bodyweight).
  • Can be given S/C (unlicenced but accepted practice)
    		•
    02.02.01 Metolazone  Tablet
  • unlicensed
  • Position statement: Can be used in combination with a loop diretic in severe heart failure. Initiation of the drug should occur after consultation with the Cardiology team. Close monitoring of renal function is required
    		•
    02.04 Metoprolol  Tablet, MR tablet,(Injection - secondary care only)
  • Heart failure- third line, where there is a perceived need to use a short acting cardioselective beta-blocker.
  • If needed tablets can be crushed and dispersed in water. Do not crush/disperse MR tablets.
    • 05.01.11 Metronidazole 
    05.04.03 Metronidazole 
    07.02.02 Metronidazole Zidoval® Vaginal gel 0.75%
  • 40g pack with 5 applicators
    		•
    13.10.01.02 Metronidazole 
    24.01 Metronidazole  Review dosing? BNFC?
    Indication:
    Anaerobic bacterial infection
    Dose:
    15 mg/kg loading dose then:
    7.5 mg/kg 12hourly(<28 days old)
    7.5 mg/kg 8hourly(>28days old)
    Administration
    IV infusion over at least 15 minutes
    Monitoring
    Liver function, FBC,
    Further Info:
    Dose may need adjusting if baby on steroids or barbituates
    Supply:
    Available from pharmacy as stock.
    13.10.01.02 Metronidazole 0.75% 
    06.07.03 Metyrapone Metopirone®
    07.02.02 Miconazole Gyno-Daktarin® Intravaginal Cream 2%
    12.03.02 Miconazole Daktarin® Oral Gel
    13.10.02 Miconazole 
    04.08.02 Midazolam 
    15.01.04.01 Midazolam  Injection 5mg/ml, 10mg/5ml
    Management of disturbed behaviour
  • Max daily dose 2.5mg-7.5mg (15mg in 24 hours)
  • Max single dose 7.5mg
    		•
    24.01 Midazolam  Indication:
    Seizures, sedation
    Dose:
    May require a loading dose
    60-150micrograms/kg/hour continous infusion
    Administration
    10mg of midazolam into 50mls glucose 5%or 10% for continous infusion
    Monitoring
    Heart rate, hypotension, hypotonia, agitation, urine output, temp and .
    Further Info:
    Can accumulate in neonates, consider reducing dose after 24hours if continuious infusion likely to continue.
    Antidote: See Flumazenil
    Supply:
    Available from pharmacy as stock. DSU can make syringes on request. Controlled drug.
    20 MIDAZOLAM buccal  
    02.07.02 MIDODRINE Tablets 2.5 mg, 5mg 
    07.01.02 Mifepristone Mifegyne® Tablet 200mg
    05.01.03 Minocycline 
    05.01.03 Minocycline Minocin® MR
    07.04.02 Mirabegron Betmiga® Capsule 25mg and 50mg
    04.03.04 Mirtazapine  Tablets 15mg, 30mg and 45mg
    Orodispersible tablets also avaialable
    01.03.04 Misoprostol Cytotec® Tablet 200 micrograms
  • Not first line for gastro protection
    		•
    07.01.01 Misoprostol  Tablets


    08.01.02 Mitomycin 
    11.99.99.99 Mitomycin C   Intravitreal Injection
    Unlicensed - prepared by aseptic unit
    08.01.02 Mitoxantrone Onkotrone®
    08.01.02 Mitoxantrone (Mitozantrone) 
    15.01.05 Mivacurium Chloride 
    04.03.02 Moclobemide  Tablets 150mg and 300mg
  • Usual dose range 150-600mg
  • Max daily dose 600mg
  • Max single dose 300mg
    		•
    04.04 Modafinil Provigil®
    12.02.01 Mometasone Furoate Nasonex® Nasal spray 50micrograms per spray
    13.04 Mometasone Furoate 0.1% Elocon® Cream, Ointment, Scalp lotion
  • Potent
    • 03.03.02 Montelukast Singulair® Tablet 10mg, Chewable tablet 5mg, Granules 4mg
    04.07.02 Morphine  Normal relase (~4 hours effect): Oral solution (e.g. Oramorph®), Tablet (Sevredol®)
    - Slow release (~12hr effect): Morphgesic Tablet MR 10mg, 30mg, 60mg, 100mg, 200mg, (MST® Tablet MR 5mg and 15mg ONLY), Injection.

    First line strong opioid
    24.01 Morphine Sulphate  Indication:
    Sedation, analgesia
    Dose:
    20 microcrams/kg/hr
    Dose range of 5 - 20 microcrams/kg/hr is normally prescribed
    Administration
    IV infusion
    Standard stock syringes are 2.5mg in 50mls glucose 5% (50micrograms/ml)
    Monitoring
    Respiratory rate, blood pressure,temperature and agitation.
    Further Info:
    Prescribe concentration, rate and dose
    Antidote: See Naloxone
    Compatibility: Glucose 5%, Glucose 10%, Sodium chloride 0.9%,Adrenaline, Aminophylline, Amiodarone, Calcium chloride, Dobutamine, Fentanyl, Insulin, Magnesium sulphate, Midazolam, Potassium chloride
    Supply:
    Available from DSU as a stock syringe. Order every Tuesday. 1mg in 50ml diluent is also available on named requests.
    24.01 Morphine Sulphate Neonatal Abstinence Syndrome Indication:
    Neonatal Abstinence Syndrome
    Dose:
    Start: 40 micrograms/kg/dose 4 hourly review daily
    Reduce as soon as tolerable to:
    30 micrograms/kg/dose 4 hourly then
    20 micrograms/kg/dose 4 hourly then
    10 micrograms/kg/dose 4 hourly then stop.
    Discuss sedative use with consultant before starting.
    Administration
    Oral solution(100micorgrams in 1ml)
    Monitoring
    Respiratory rate, blood pressure,temperature and agitation.
    Further Info:

    Supply:
    Available from DSU as a stock item. M2(TCU) hold stock for OOH use.
    01.06.05 Moviprep®  Oral powder sachets
    Restricted to use as a bowel prep prior to colonoscopy
    05.01.12 Moxifloxacin  For frug resistant Tuberculosis, seek advice from infectious diseases
    05.01.12 Moxifloxacin 
    02.05.02 Moxonidine  Tablet
  • Restricted for resistant or refractory cases
  • If needed tablets can be crushed and dispersed in 50ml water. Crush thoroughly and disperse well before administering to prevent tube blockage.
    • 09.06.07 Multivitamin  
    09.06.07 Multivitamin preparations Dalivit®
    09.06.07 Multivitamin preparations Abidec®
    13.10.01.01 Mupirocin  Ointment and Cream
    08.02.01 Mycophenolate Mofetil CellCept®
    08.02.01 Mycophenolate Sodium Myfortic®
    02.06.04 Naftidrofuryl Oxalate 
    15.01.07 Naloxone 
    18 Naloxone 
    04.10.03 Naltrexone 
    10.01.01 Naproxen 
    • Tablets 250mg, 500mg.
    12.02.03 Naseptin® Chlorhexidine Hydrochloride 0.1%, Neomycin Suphate 0.5%

    Cream

    • Should not be used in patients with a peanut allergy
    • MRSA suppression: Four times daily for 10 days
    08.02.04 Natalizumab Tysabri®
    02.04 Nebivolol Nebilet® Tablet
  • Specialist initiation only
  • Tablets can be crushed and mixed with water for administration
    		•
    11.04.02 Neodocromil Rapitil® Eye drops 2%
    10.02.01 Neostigmine 
    15.01.06 Neostigmine 
    15.01.06 Neostigmine with Glycopyrronium 
    02.06.03 Nicorandil  Tablet 10mg and 20mg
  • If needed tablets can be crushed and dispersed in water
    		•
    04.10 Nicotine Nicotinell®
    04.10.02 Nicotine 
    02.06.02 Nifedipine  Tablets, MR tablets, capsules, MR capsules
  • Prescribe by brand according to medicines policy
    		•
    08.01.05 Nilotinib Tasigna®
    02.06.02 Nimodipine Nimotop® Tablet
  • Injection- use Polyethylene (PE) giving set for infusion (NOT PVC!)
  • Specialist use in secondary care only
  • If needed tablets can be crushed and dispersed in water. Give immediately as rapid degradation occurs.
    		•
    04.01.01 Nitrazepam  Tablets 5mg, suspension 2.5mg/5ml
  • Usual dose range: 5-10mg at night
  • Max daily dose 10mg
  • Max single dose 10mg
    		•
    05.01.13 Nitrofurantoin 
    15.01.02 Nitrous oxide 
    08.01 Nivolumab Opdivo®
  • For use in line with NICE TA384, TA400 & TA417
    		•
    02.07.02 Noradrenaline / Norepinephrine  Injection (secondary care only)
    06.04.01.02 Norethisterone  Tablet 5mg
    08.03.02 Norethisterone 
    14.05.01 Normal immunoglobulin for Intramuscular use 
    14.05.01 Normal immunoglobulin for Intravenous use 
    14.05.01 Normal immunoglobulin for Subcutaneous use 
    04.03.01 Nortriptyline 
    06.01.01.01 NovoRapid® Insulin Aspart
  • Rapid acting recombinant human insulin analogue
  • 10mL vial
  • 3mL Penfill® cartridge for NovoPen® devices
  • 3mL prefilled Flexpen®
  • 3ml prefilled FlexTouch® pen
    		•
    A2.05.02 Nutilis® Powder 
    • For adult renal patients or patients on a sodium restricted diet
    • Contact the speach and language therapists (SALT) team for futher information and advice
    13.04 Nystaform-HC®  Cream, Ointment
    Mild with antimicrobial
  • Cream contains 0.5% hydrocortisone, Ointment contain 1%
  • useful for facial eczema in children
    		•
    12.03.02 Nystatin Nystan® Oral suspension 100 000 units per mL
    13.10.02 Nystatin 
    24.01 Nystatin  Indication:
    Prophylaxis for ventilated babies < 1500g with central lines.
    Treatment of oral and perioral fungal infections
    Dose:
    Prophylaxis: 50,000units TDS
    Treatment: 100,000units QDS usually for 7 days, and continued for 48 hours after lesions have healed.
    Administration
    Oral
    Monitoring

    Further Info:
    Document on drug chart indication(Prophylaxis or treatment)
    If bottle or breast fed administer after feed.
    Consider treament for breast feeding mums.
    Supply:
    Available from pharmacy as a stock item.(100,000units in 1ml)
    13.10.02 Nystatin 100,000 uints/g Nystan®
    13.10.02 Nystatin with Chlorhexidine cream Nystaform®
    01.09.01 Obeticholic acid Ocaliva®
  • Restricted for treatment of primary biliary cholangitis (also known as primary biliary cirrhosis) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA or as monotherapy in adults unable to tolerate UDCA.
    		•
    11.08.02 Ocriplasmin Jetrea®
    13.11 Octenisan® 

    Skin antisepsis

    • For patients requiring prolonged use or recurrent applications (due to multiple admissions), those with sensitive skin or immobile bedbound patients
    • MRSA suppression: use once daily for duration of admission
    08.03.04.03 Octreotide Sandostatin®
    08.03.04.03 Octreotide Sandostatin Lar®
    06.04.01.01 Oestrogen only HRT gel Oestrogel®
    06.04.01.01 Oestrogen only HRT patch Estradot®, Evorel®
    06.04.01.01 Oestrogen only HRT tablet Elleste-Solo®, Premarin®
    06.04.01.01 Oestrogens for HRT Elleste-Solo® MX
    07.02.01 Oestrogens, Topical Gynest® Intravaginal cream: estriol 0.01% (10x weaker than Ovestin)
    07.02.01 Oestrogens, Topical Ovestin® Intravaginal cream: estriol 0.1% (10x stronger than Gynest)
    07.02.01 Oestrogens, Topical Vagifem® Vaginal tablet: estradiol 10mcg
  • 25 mcg strength was discontinued end 2012. 10mcg considered as efficacious
    • 08.02.03 Ofatumumab Arzerra®
    05.01.12 Ofloxacin 
    11.03.01 Ofloxacin Eye drops Exocin® eye drops 0.3%
    13.02.01 Oilatum®  Cream, Shower gel, emmolient bath oil
    13.02.01.01 Oilatum® Plus  emollient bath additive
    01.07.03 Oily phenol injection BP  Injection
    04.02.01 Olanzapine Zyprexa® Tablets 2.5mg, 5mg, 10mg, 15mg, 20mg ; dispersible tablets also available (significantly more expensive)
  • second generation antipsychotic
  • Usual dose range 5-20mg daily
  • Max daily dose 20mg
  • Max single dose 20mg
    		•
    04.02.02 Olanzapine Embonate ZypAdhera®
    12.01.03 Olive Oil Ear Drops  Drops
    03.04.02 Omalizumab Xolair® Specialist use only
    13.05.03 Omalizumab Xolair

    As per NICE guidelines:

    TA339: Omalizumab for previously treated chronic spontaneous urticaria
    02.12 Omega-3-Acid Ethyl Esters Omacor®
    01.03.05 Omeprazole 
  • Capsules first line 10mg, 20mg and 40mg
  • Capsules can be opened and beads swallowed without crushing, or can be mixed with food or drink

  • Restricted Item orodispersible tablets restricted for use in patients with swallowing difficulties or who are on enteral tube feeding and first choice lansoprazole is not suitable

    		•
    01.03.05 Omeprazole IV  Restricted as per guideline - See Upper GI Bleeds Clinical Pathway (below)
    04.06 Ondansetron 

    Tablets, injection, syrup and orodispersible film.
    04.09.01 Opicapone Ongentys®
  • 2nd line where entacapone not appropriate, tolerated or effective or in those with mild-moderate liver impairment
    		•
    07.03.02.01 Oral Progestogen Only Contraceptives Cerazette®, Zelleta® Prescribe by brand, Zelleta® preferred brand at BTHFT
    07.03.02.01 Oral Progestogen Only Contraceptives Micronor®
    07.03.02.01 Oral Progestogen Only Contraceptives Norgeston®
    07.03.02 Oral Progestogen-Only Contraceptives Femulen® Tablet, etynodiol diacetate 500 micrograms
    07.03.02 Oral Progestogen-Only Contraceptives Norgeston®
    07.03.02 Oral Progestogen-Only Contraceptives Cerazette®
    07.03.02 Oral Progestogen-Only Contraceptives Micronor® Tablet, norethisterone 350 micrograms
    09.02.01.02 Oral Rehydration Salts Dioralyte® oral powder
    08.01.05 Oxaliplatin 
    11.07 Oxybuprocaine Hydrochloride Minims®
    07.04.02 Oxybutynin  Tablet 2.5mg and 5mg
    Modified release 5mg and 10mg
    07.04.02 Oxybutynin Hydrochloride Kentera® Patch 36mg (releasing approx 3.9mg/24 hours)
  • Change patch twice weekly (every 3-4 days)
    		•
    04.07.02 Oxycodone  Normal release: Capsule (OxyNorm), Liquid, Concentrate liquid, Injection
    Slow release: Tablet (OxyContin)

  • Not first line strong opioid
  • More expensive, and not superior to morphine. Only for patients unable to tolerate idiosyncratic side effects with morphine.
  • Always give prophylactic laxatives
    		•
    05.01.03 Oxytetracycline 
    13.06.02 Oxytetracycline  Tablets 250mg
    07.01.01 Oxytocin Syntocinon® Injection 5units/ml
    08.01.05 Paclitaxel Abraxane® NAB-Paclitaxel- Normal Albumin Bound – Paclitaxel .
    Dosing NOT interchangeable with “normal” paclitaxel

    Used in Combination with Gemcitabine for Pancreatic Cancer – VIA CDF
    Approved for Breast Cancer
    08.01.05 Paclitaxel 
    04.02.02 Paliperidone Xeplion®
    05.03.05 Palivizumab Synagis®
    04.06 Palonosetron with netupitant Akynzeo®
    • Palonosetron 0.5mg with netupitant 300mg
    • For use by oncology team only
    • Anti-emetic for use with cancer chemotherapy
    04.06 Palonosetron with netupitant Akynzeo®
    • Palonosetron 0.5mg with netupitant 300mg
    • For use by oncology team only
    • Anti-emetic for use with cancer chemotherapy
    01.09.04 Pancreatin Creon® Micro Granules
  • Only for paediatrics
  • All pancreatin products contain pancreatin from a porcine source, currently an alternative is not available.
    • 01.09.04 Pancreatin Creon® 10000, 25000, 40000 Capsule
  • All pancreatin products contain pancreatin from a porcine source, currently an alternative is not available.
    • 24.01 Pancuronium  Indication:
    Muscle relaxation
    Dose:
    100-200 micrograms/kg/dose PRN
    Administration
    IV bolus over 30seconds
    Dilute 1ml to 10ml with sodium chloride 0.9% or glucose 5% (200micrograms in 1ml)
    Monitoring
    Blood pressure, ventilation requiremnts may increase.
    Further Info:
    Longer acting than atracurium
    Antidote: See Neonatal Formulary 6th Ed
    Supply:
    Available from pharmacy as stock (2000 micrograms in 1ml)
    15.01.05 Pancuronium Bromide 
    08.01.05 Panitumumab  
  • For use in line with NICE TA439
  • Patient Access Scheme available for this treatment (in line with NICE TA439)
    		•
    01.03.05 Pantoprazole  Tablets, 20mg and 40mg
    01.03.05 Pantoprazole IV  Restricted as per guideline - See Upper GI Bleeds Clinical Pathway (below)
    04.07.01 Paracetamol Perfalgan®
    04.07.01 Paracetamol  Tablet, Soluble tablet, Injection, Liquid, Suppositories
  • The dose of IV paracetamol should be reduced in patients weighing less than 50Kg, the dose should be calculated as 15mg/kg four times a day.
  • The maximum daily infusion dose should be 3g in patients greater than 50 kg body-weight who have risk factors for hepatotoxicity such as: alcohol dependence; hepatocellular insufficiency, chronic alcoholism, chronic malnutrition, or dehydration.
    		•
    24.01 Paracetamol  Indication:
    Analgesia for mild to moderate pain.
    Dose:
    IV
    Preterm: >32/40 7.5mg/kg every 8hours(Max 25mg/kg in 24hours)
    Term: 10mg/kg every 4-6 hours(Max 30mg/kg in 24hours)
    Oral
    Preterm 28-32/40 10-15mg/kg every 8 to 12 hours(Max 30mg/kg in 24hours)
    Preterm >32/40 10-15mg/kg every 6 to 8 hours(Max 60mg/kg in 24hours)
    Indicate maximum daily dose in 24hours on chart
    Administration
    IV infusion over 15minutes
    Monitoring
    Blood pressure,heart rate(tachycardia),Liver Function,
    Renal function
    Further Info:
    Give undiluted or dilute to a concentration of not less than 1 mg/mL in Glucose 5% or Sodium Chloride 0.9%; use within 30minutes of dilution
    Supply:
    Available from pharmacy as a name pateint request.
    Supplied as 500mg in 50ml vial (10mg/ml)
    04.07.01 Paracetamol and codeine Co-codamol® 8/500 Tablet, Soluble tablet.
    04.07.01 Paracetamol and codeine Co-codamol® 30/500 Tablet, Effervescent tablet
    15.01.04.02 Parecoxib Dynastat®
    24.03 Parenteral Nutrition  See current sharepoint protocol
    09.06.04 Paricalcitol 
    04.03.03 Paroxetine  Tablets 10mg, 20mg and 30mg
  • Usual dose range 20-50mg daily
  • Max daily dose 50mg
  • Max single dose 50mg
    		•
    09.02.01.01 Patiromer sorbitex calcium Veltassa®
    • 8.4g and 16.8g sachets
    • For treatment of acute and chronic hyperkalaemia
    14.04 Pediacel® 
    08.02.04 Peginterferon Alfa Pegasys® Initiated by hepatitis specialist team
    08.02.03 Pembrolizumab KeyTruda®
  • For use in line with NICE TA357, NICE TA366, NICE TA428 & TA447
    		•
    08.01.03 Pemetrexed Alimta® Maintenance pemetrexed available through the CDF
    09.08.01 Penicillamine 
    10.01.03 Penicillamine 
    08.01.05 Pentostatin Nipent®
    01.02 Peppermint Oil  Colpermin®
  • Colpermin brand contains arachis (peanut) oil
  • Peppermint oil 0.2ml
  • Capsule, MR, EC

    Mintec®
  • Peppermint oil 0.2ml
  • Capsule, EC
    		•
    01.02 Peppermint water  Solution unlicensedunlicensed
    04.08.01 Perampanel Fycompa®
    • For initiation by consultant neurologist only
    13.10.04 Permethrin 1% Lyclear® Creme Rinse
    13.10.04 Permethrin 5%  Dermal Cream
    08.01.05 Pertuzumab Perjeta® 1st line treatment of locally advanced or metastatic breast cancer
    04.07.02 Pethidine  Tablet, Injection
  • preferred in obstetrics
    		•
    04.03.02 Phenelzine  Tablets 15mg
  • Usual dose range :aim for lowest possible maintenace dose
  • Max daily dose 90mg
  • Max single dose 30mg
    • 02.08.02 Phenindione  Tablet
  • For patients intolerant of warfarin
    • 04.08.01 Phenobarbital 
    04.08.02 Phenobarbital 
    24.01 Phenobarbital Phenobarbitone Indication:
    Seizures
    Dose:
    20 mg/kg loading dose
    5 mg/kg/day maintenance
    Administration
    IV over at least 20minutes(no faster than 1mg/kg/minute)
    Take 1ml of 200mg/ml and dilute to 10ml with water for injection(20mg in 1ml)
    Monitoring
    Blood pressure(Hypotension, respiratory rate
    Blood Levels 20 - 40mg/l
    Further Info:

    Supply:
    Available from pharmacy as stock (200mg in 1ml)
    02.05.04 Phenoxybenzamine Hydrochloride  Capsules
  • Specialist use only for hypertensive episodes in phaeochromocytoma
    • 05.01.01.01 Phenoxymethylpenicillin 
    A2.07 Phenylalanine Amino Acid Supplement 
    02.07.02 Phenylephrine  Injection not stocked within BTHFT
    11.05 Phenylephrine Hydrochloride  Minims®Phenylephrine Hydrochloride 2.5% and 10% single use eye drops
    04.08.01 Phenytoin 
    04.08.01 Phenytoin Epanutin®
    24.01 Phenytoin  Indication:
    Seizures
    Dose:
    IV
    Loading dose 15 mg/kg
    Maintenance 2.5 mg/kg bd
    Administration
    IV(ideally centrally) over at least 15 mins(Max rate 1mg/kg/min)
    May be diluted if required using sodium chlorde 0.9% ONLY to a maximium concentration of 10mg in 1ml. A filter of 0.22 -0.5micron must be used for diluted IV phenytoin.
    Monitoring
    Metabolism increases over 5-7 weeks then stabilises, dosage increases will be necessary during this time. Monitor levels
    Trough level 40-80 mmols/L or 6-15mg/L
    Further Info:
    Not compatible with glucose. Flush line with sodium chloride 0.9% before and after administratrion.
    Oral dose should only be given 30minutes before or after feeds.
    Supply:
    Available from pharmacy as a stock item.
    03.09.01 Pholcodine Linctus, BP  Linctus
  • for a dry cough
    		•
    09.05.02.01 Phosphate supplements Phosphate-Sandoz® Effervescent tablet
  • Contains 16.1mmol phosphate, 20.4mmol sodium and 3.1mmol potassium per tablet

    		•
    01.06.04 Phosphates (Rectal) Fleet® Ready to use Enema Enema
    09.06.06 Phytomenadione 
    09.06.06 Phytomenadione Konakion® MM
    09.06.06 Phytomenadione Konakion® MM Paediatric
    11.06 Pilocarpine  Eye drops 1% and 2%
    Minims single use 2%
    12.03.05 pilocarpine Hydrochloride Salagen®
    11.06 Pilocarpine preservative free 
    13.05.03 Pimecrolimus Elidel® Cream 1%
    06.01.02.03 Pioglitazone Actos® Tablets 15mg, 30mg, 45mg
    05.01.01.04 Piperacillin and Tazobactam 
    04.02.02 Pipotiazine Palmitate Piportil® Depot Depot injection
    04.09.03 Piracetam Nootropil®
    • Restricted for initiation by or on the advice of a consultant paediatric neurologist
    10.01.01 Piroxicam 
    10.03.02 Piroxicam 
    • 0.5% gel
    05.01.01.05 Pivmecillinam Hydrochloride Selexid®
    04.07.04.02 Pizotifen  Tablets 0.5mg and 1.5mg
    09.01.07 Plerixafor 
    14.04 Pneumococcal polysaccharide conjugate vaccine (adsorbed) Prevenar 13®
    14.04 Pneumovax® II 
    13.07 Podophyllotoxin Condyline®
    13.07 Podophyllotoxin Warticon®
    06.01.06 Polycal®  Powder
  • Available for Glucose Tolerance Test. To be given as 113ml Polycal® liquid diluted with water to a total volume of 200-300ml (see BNF).

    • 09.02.01.01 Polystyrene sulphonate resins Calcium Resonium®
    • 300g tub. Includes a 15g scoop
    • For treatment of acute and chronic hyperkalaemia

     

    • Due to be replaced by patiromer sorbitex calcium (Veltassa®)
    13.09 Polytar® 
  • Discontinued
    		•
    11.08.01 Polyvinyl Alchohol SnoTears® Eye drops
    08.02.04 Pomalidomide 
    08.01.05 Ponatinib Iclusig®
  • For use in line with NICE TA451
    		•
    03.05.02 Poractant Alfa Curosurf® Suspension
  • For specialist use only
  • Porcine lung extract
    		•
    05.02 Posaconazole Noxafil®
    09.02.01.01 Potassium Chloride Kay-Cee-L® Syrup
  • 1mL = 1mmol of K+

    • 09.02.01.01 Potassium Chloride Sando-K® Tablet
  • 1 tablet = 12mmol of K+
    • 09.02.02.01 Potassium Chloride and Glucose Intravenous Infusion   Available in multiple strengths
  • Potassium Chloride 10mmol in 500mL with Dextrose 5% (20mmol per litre)
  • Potassium Chloride 10mmol in 500mL with Dextrose 10% (20mmol per litre)
  • Potassium Chloride 20mmol in 500mL with Dextrose 5% (40mmol per litre)
  • Potassium Chloride 20mmol in 500mL with Dextrose 10% (40mmol per litre)
  • Potassium Chloride 20mmol in 1000mL with Dextrose 5% (20mmol per litre)
  • Potassium Chloride 40mmol in 500mL with Dextrose 5% (80mmol per litre)
  • Potassium Chloride 40mmol in 1000mL with Dextrose 5% (40mmol per litre)
    • 09.02.02.01 Potassium Chloride, Sodium Chloride and Glucose Intravenous Infusion  Available in multiple strengths
  • Potassium Chloride 10mmol in 500mL with Dextrose 4% & Sodium Chloride 0.18% (20mmol per litre)
  • Potassium Chloride 10mmol in 500mL with Dextrose 5% & Sodium Chloride 0.45% (20mmol per litre)
  • Potassium Chloride 20mmol in 500mL with Dextrose 5% & Sodium Chloride 0.45% (40mmol per litre)
  • Potassium Chloride 20mmol in 1000mL with Dextrose 2.5% & Sodium Chloride 0.45% (20mmol per litre)
  • Potassium Chloride 20mmol in 500mL with Dextrose 4% & Sodium Chloride 0.18% (40mmol per litre)
  • Potassium Chloride 20mmol in 1000mL with Dextrose 4% & Sodium Chloride 0.18% (20mmol per litre)
  • Potassium Chloride 40mmol in 1000mL with Dextrose 4% & Sodium Chloride 0.18% (40mmol per litre)
    • 07.04.03 Potassium Citrate  Oral solution , potassium citrate 30% and citric acid 5%
  • 10ml TDS well diltuted with water for alkalinsation of urine
    Sachets also available
    		•
    13.11.06 Potassium Permanganate Permitabs®
    13.11.04 Povidone-Iodine Betadine® or Videne®
    13.11.04 Povidone-Iodine Savlon® Dry Antiseptic
    04.09.01 Pramipexole 
    02.09 Prasugrel  Tablet (position statement from cardiology to add)
    02.12 Pravastatin   Tablet
  • If needed tablets can be crushed and dispersed in water
    		•
    02.05.04 Prazosin 
    01.05.02 Prednisolone 


     
    01.05.02 Prednisolone 
    • Tablets
    06.03.02 Prednisolone  Tablets 1mg, 2.5mg, 5mg, 25mg and soluble Tablets 5mg

  • EC tablets 6x the price of plain tablets without any substantial evidence that they confer any GI benefits
  • Soluble tablets 15x more expensive than normal tablets
    		•
    08.02.02 Prednisolone 
    11.04.01 Prednisolone  Eye drops
  • 0.5% Predsol® (eye and ear drops); Minims® Prednisolone Sodium Phosphate(Bausch & Lomb)
  • 1% Pred Forte®
    		•
    12.01.01 Prednisolone 0.5% with Neomycin 0.5% Predsol-N® Discontinued in the UK
    11.04.01 Prednisolone 0.5% with Neomycin 0.5% Predsol-N®
    12.01.01 Prednisolone ear drops Predsol® Drops 0.5%
    11.04.01 Prednisolone preservative free eye drops 
    04.02.03 Pregabalin  Capsules 25mg, 75mg, 150mg, 225mg and 300mg
    For generalised anxiety disorder
  • Usual dose range 150-600mg daily in two to three divided doses
  • max daily dose 600mg
  • max single dose 300mg
    • 04.07.03 Pregabalin  Capsule
  • Should only be considered after both amitriptyline and gabapentin have failed at optimised doses.
  • If needed capsules can be opened and contents dispersed in water.


    • 04.08.01 Pregabalin 
    15.02 Prilocaine Hydrochloride Citanest®
    04.08.01 Primidone Mysoline®
    10.01.04 Probenecid 
    24.01 Probiotic Infloran®

    Indication:

    Prevention of necrotizing enterocolitis (NEC)

    Dose:

    1/2 capsule ONCE a day with feeds

    Administration:

    Add Infloran to 2ml milk or water (1 capsule) (EBM / donor or formula) prior to feeds.

    Administer half the volume.

    If administered mixed with water, give additional to feeds.

    Further Info:

    As soon as a baby has commenced enteral feeds, and is thought to be tolerating 0.5mls/h of milk.         

    Probiotics can be stopped once the baby is 34 weeks corrected gestation providing the baby has been tolerating enteral feeds for the 2 weeks prior to this date

    Supply:

    Available on NNU as a stock item.

     

    Stored in Fridge

     
    08.01.05 Procarbazine 
    04.02.01 Prochlorperazine 
    04.06 Prochlorperazine  Tablet
    Buccal tablet
    Injection (IM route only. Not for IV or SC use.)
    04.06 Prochlorperazine Buccastem® (Bucal preparation)
    01.07.02 Proctosedyl  Ointment and Suppository
  • Ointment - cinchocaine 0.5% and hydrocortisone 0.5%
  • Suppositories - cinchocaine 5mg and hydrocortisone 5mg
    		•
    04.09.02 Procyclidine 
    13.10.05 Proflavine Cream, BPC  
    06.04.01.02 Progesterone Cyclogest® pessaries 200mg and 400mg
    06.04.01.02 Progesterone Gestone®
    04.02.01 Promazine Hydrochloride Promazine® Tablet 25mg, Oral solution 25 mg/5 mL
  • First generation antipsychotic
  • Usual dose range 100-200mg up to four times daily
  • Max daily dose 800mg
  • Max single dose 200mg
    		•
    03.04.01 Promethazine  Tablets 10mg, 25mg, Liquid 5mg/5ml, Injection 25mg/ml

    Promethazine Teoclate (avomine) preferred in pregnancy rather than Promethazine Hydrochloride
    04.06 Promethazine Hydrochloride Phenergan Tablets 10mg and 25mg
    04.01.01 Promethazine Hydrochloride  Tablets 10mg, 25mg
  • Usual dose range: 10-25mg at night
  • Max daily dose 50mg
  • Max single dose 50mg
    		•
    13.11 Prontoderm® Foam 

    Skin antisepsis

    • For patients requiring prolonged use or recurrent applications (due to multiple admissions), those with sensitive skin or immobile bedbound patients

    • MRSA suppression: use once daily for duration of admission
    12.02.03 Prontoderm® Nasal Gel 

    Nasal gel

    • For patients who cannot use Naseptin® nasal cream while Bactroban® is unavailable
    • MRSA suppression: Three times daily for 5 days
    02.03.02 Propafenone  Cardiology use only
    11.03.01 Propamidine Isetionate Brolene® Eye drops 0.1%
    15.01.01 Propofol 
    15.01.01 Propofol Diprivan®
    02.04 Propranolol  Tablet, Capsule MR, Liquid, (Injection - secondary care only)
  • If needed MR capsules can be opened and beads mixed with water - do not crush.
    • 04.07.04.02 Propranolol  Tablets 10mg, 40mg
    06.02.02 Propylthiouracil  Tablets 50mg
    02.08.03 Protamine Sulphate  Injection (secondary care only)
  • Remember maximum dose is 50mg.
  • To be given by slow intravenous injection over 10 minutes.
    		•
    11.07 Proxymetacaine Hydrochloride Minims® Eye drops
    11.07 Proxymetacaine Hydrochloride 0.5% with Fluorescein Sodium 0.25% Minims® Eye drops
    01.06.07 Prucalopride Resolor ® Tablet

    Restricted to gastroenterology consultant initiation for treatment of chronic, resistant constipation in WOMEN in line with NICE guidance (see below)
    05.01.09 Pyrazinamide 
    10.02.01 Pyridostigmine Bromide Mestinon®
    09.06.02 Pyridoxine Hydrochloride 
    04.02.01 Quetiapine Seroquel® Tablets 50mg, 100mg, 150mg, 300mg, 400mg. Modified release (XL) tablets also available, but siginificantly more expensive
    Second generation anitpsychotic
  • Usual dose range 300mg-600mg
  • max daily dose 800mg plain tablets or 800mg XL

    		•
    06.07.01 Quinagolide Norprolac® Tablets 75 microgram (white)
    Starter pack contains 3 x 25microgram (pink) with 3 x 50microgram (blue)
    05.04.01 Quinine 
    10.02.02 Quinine 
    06.04.01.01 Raloxifene Hydrochloride Evista® Tablet 60mg
    08.01.03 Raltitrexed Tomudex®
    02.05.05.01 Ramipril  Capsule, Oral solution
  • If needed capsules can be opened and the contents mixed with water.
    Restricted Item Oral solution, for genuine swallowing difficulties or NG tubes
    		•
    11.08.02 Ranibizumab Lucentis® Intravitreal injection
    01.03.01 Ranitidine  Tablet 150mg and 300mg, soluble tablet 150mg and 300mg, Syrup 75mg/5ml, Injection 25mg/ml
    24.01 Ranitidine  IV 500mcg/kg slow bolus qds
    or
    IV infusion 125 mcg/kg/hour
    or
    oral 2 mg/kg tds
    02.06.03 Ranolazine  Tablets 375mg and 500mg
  • following specialist recommendation
    		•
    04.09.01 Rasagiline Azilect®
    10.01.04 Rasburicase Fastertec®
    04.03.04 Reboxetine Edronex® Tablets 4mg
  • Usual dose range 4mg twice daily
  • Max daily dose 12mg
  • Max single dose 6mg
    		•
    15.01.04.03 Remifentanil 
    06.01.02.03 Repaglinide  Tablets 0.5mg, 1mg and 2mg
    A2.05.02 Resource® ThickenUp Clear 
    • To be lauched as first line thickener for adult patients November 2018
    • Contact the speach and language therapists (SALT) team for futher information and advice
    04.08.01 Retigabine 
    14.04 Revaxis® 
    05.03.05 Ribavirin 
    05.01.09 Rifampicin 
    05.01.09 Rifampicin and Isoniazid Rifinah® 300
    05.01.09 Rifampicin and Isoniazid Rifinah® 150
    05.01.09 Rifampicin and Isoniazid and Pyrazinamide Rifater®
    05.01.09 Rifampicin, isoniazid, pyrazinamide and ethambutol Voractiv®
    04.09.03 Riluzole 
    11.04.01 Rimexolone Vexol® Eye drops 1%
    13.05.03 Risankizumab Skyrizi

    As per NICE guidelines:

    TA596: Risankizumab for treating moderate to severe plaque psoriasis
    06.06.02 Risedronate 
    04.02.01 Risperidone Risperdal® Tablets,500 micrograms,1 mg, 2 mg, 3 mg, 4 mg, 6 mg
    Orodispersible tablets also available
    Liquid 1 mg/mL
    Note Liquid may be diluted with any non-alcoholic drink, except tea
  • Second generation antipsychotic
  • Initially 2mg daily Usual dose range 4-6mg daily
  • Max daily dose 16mg, no benefit generally seen above 10mg daily
    		•
    04.02.02 Risperidone Risperdal Consta®
    05.03.01 Ritonavir Norvir®
    08.02.03 Rituximab MabThera®
    10.01.03 Rituximab (rheumatology) MabThera®
    02.08.02 Rivaroxaban  Treatment of DVT or PE:
  • GPs may initiate in line with local guidance.
  • Treatment of ACS:
    - Specialist initiation only, awaiting local guidance

    GPs may continue after specialist initiation. See Primary care guideline and prescribing information sheet

    Prophylaxis of VTE post hip and knee replacement surgery:
    Complete course will be supplied by hospital, to start upon discharge. Post-op whilst in-patient to be treated with parenteral anticoagulants

  • If needed tablets can be crushed and dispersed in water.
    		•
    04.11 Rivastigmine Exelon® Tablets 1.5mg and 3mg, Patches 4.6mg/24hours and 9.5mg/24hours
    Second Line for Mild to moderate Alzheimers disease
  • Usual dose range 3-6mg twice daily (oral) and 4.6-9.5mg/24hour patch
  • Max single dose 12mg (oral) and 9.5mg/24hr patch
    		•
    15.01.05 Rocuronium Bromide 
    09.01.04 Romiplostim  Injection
  • Restriced for use in line with NICE guidelines
    		•
    04.09.01 Ropinirole 
    15.02 Ropivacaine Hydrochloride Naropin®
    11.08.02 Rose Bengal Minims® Rose Bengal
    02.12 Rosuvastatin  Tablet
  • Restricted for 3rd line use by consultants and SpRs in hypercholesterolaemia clinic and cardiology

    • 14.04 Rotavirus vaccine Rotarix®
    04.08.01 Rufinamide Inovelon® Tablets
  • specialist use only
    		•
    08.01.05 Ruxolitinib Jakavi®
    03.01.01.01 Salbutamol  Short acting beta agonist
    The following formulations are available on formulary: MDI, breath actuated MDI, DPI, nebules, tablets, MR capsules, injection

  • 1st line = MDI + spacer
  • 2nd line = CFC free breath actuated (Salamol Easi-Breathe - prescribe by brand)
  • 3rd line = DPI (Easyhaler® Salbutamol)
  • Nebules also available. Nebs may be diluted with 0.9% sodium chloride if needed

    • 03.01.01.01 Salbutamol Ventmax® SR
    13.05.02 Salicyclic acid 2% and zinc 24% paste 
    13.07 Salicylic Acid 16.7% with Lactic Acid 16.7% Salactol®
    13.05.02 Salicylic Acid in White Soft Paraffin 
    03.01.01.01 Salmeterol 
  • Long acting beta-agonist
  • Evohaler (25mcg/dose) and Accuhaler (50mcg/dose) available
    		•
    09.05.01.01 Sandocal-1000®  Effervescent tablet
  • Each tablet contains 2263mg of calcium lactate gluconate and 1750mg of calcium carbonate (equivalent to 1000mg or 25mmol of calcium)
    		•
    05.03.01 Saquinavir Invirase®
    01.07.02 Scheriproct®   Suppositories and ointment
  • Contains Cinchocaine 0.5% and prednisolone 0.19%
    		•
    10.01.03 Secukinumab Cosentyx® For use in line with NICE guidance for treatment of:
  • Psoriatic arthritis
  • Ankylosing spondylitis
    For use in plaque psoriasis, see section 13.5.3
    		•
    13.05.03 Secukinumab Cosentyx®

    For use in line with NICE guidance:

    TA350: Secukinumab for treating moderate to severe plaque psoriasis

    TA445: Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs
    04.09.01 Selegiline Hydrochloride 
    09.05.05 Selenium Selenase® IV injection
  • TPN team
    • 06.01.02.03 Semaglutide Ozempic®
    • First choice glucagon-like peptide-1 receptor agonist in parimary care
    01.06.02 Senna  Tablet 7.5mg, Syrup 7.5mg/5ml
    04.03.03 Sertraline  Tablets 50mg, 100mg
  • Usual dose range 50-200mg daily
  • Max daily dose 200mg
  • Max single dose 200mg
    		•
    09.05.02.02 Sevelamer Carbonate Renvela® Powder for oral suspension (sachets)
    09.05.02.02 Sevelamer Hydrochloride  Renagel® Tablets
    15.01.02 Sevoflurane 
    13.09 Shampoos Ceanel Concentrate®
    02.05.01 Sildenafil  Tablet

    Secondary care only for pulmonary arterial hypertension (PAH) Revatio 20mg not stocked only keep sildenafil 25mg tablets.
    NOT for erectile dysfunction (ED)
    07.04.05 Sildenafil 
    13.07 Silver Nitrate AVOCA®
  • caustic pencil, tip containing silver nitrate 40%, potassoim nitrate 60%
    		•
    13.10.01.01 Silver Sulfadiazine Flamazine® Cream
    05.03.03.02 Simeprevir Olysio
    First line for Genotype I and IV, in accordance with NHS England policy and NICE
    01.01.01 Simeticone  Infacol® For paediatrics and gastroenterology use
    03.09.02 Simple Linctus, BP  Linctus

  • Considered to be of limited clinical value. May be prescribed if appropriate in secondary care

    		•
    03.09.02 Simple Linctus, Paediatric BP 
    02.12 Simvastatin  Tablets
  • If needed tablets can be crushed and dispersed in water. Poorly soluble and degrades rapidly so crush thoroughly and give immediately
    		•
    08.02.02 Sirolimus Rapamune®
    06.01.02.03 Sitagliptin Januvia® Tablets 25mg, 50mg and 100mg
    09.08.01 Sodium Benzoate  
    09.02.01.03 Sodium Bicarbonate  Capsule (500mg = approx. 6 mmol each of Na+ and HCO3-)
  • Capsules can be opened and the contents dispersed in water.
    		•
    09.02.02.01 Sodium Bicarbonate  Available in multiple strengths:
  • Sodium Bicarbonate 1.26% 500ml polyfusor (supply problems - probably not available)
  • Sodium Bicarbonate 1.4% 500ml polyfusor (supply problems - probably not available)
  • Sodium Bicarbonate 4.2% 10ml ampoules or 500ml polyfusor
  • Sodium Bicarbonate 8.4% 10ml ampoules or 500ml polyfusor
    		•
    12.01.03 Sodium Bicarbonate  Ear drops
    24.01 Sodium Bicarbonate  2-3 mmol/kg by slow infusion 8.4%sodium bicarbonate = 1mmol/ml
    Dilute with water Monitor infusion site closely, extravasation can cause severe tiisue damage
    18 Sodium calcium edetate 
    09.02.01.02 Sodium Chloride Slow Sodium®
    11.08.01 Sodium Chloride 
    11.08.01 Sodium Chloride Minims® Saline Eye drops 0.9% (preservative free)

    13.11.01 Sodium Chloride 0.9% 
    11.08.01 Sodium Chloride 0.9% Solutions 
    09.02.02.01 Sodium Chloride Intravenous  Available in multiple strengths.
    Infusions:
  • Sodium Chloride 0.45% infusion 500ml bag or polyfusor
  • odium Chloride 0.9% infusion 50ml, 100ml, 250ml, 500ml, 1 litre
  • Sodium Chloride 1.8% infusion 500ml
  • Sodium Chloride 2.7% infusion 500ml polyfusor

    Ampoules:
  • Sodium Chloride 0.9% injection 2ml, 5ml, 10ml and 20ml ampoules
  • Sodium Chloride 30% injection 10ml
    • 07.04.03 Sodium Citrate 
    07.04.04 Sodium Citrate 
    06.06.02 Sodium Clodronate  Tablet 800mg
    11.04.02 Sodium Cromoglicate  Eye drops 2%
    09.01.01.01 Sodium Feredetate Sytron® Elixir
  • Sodium feredetate 190 mg equivalent to 27.5 mg of iron/5 mL
    • 11.08.01 Sodium Hyaluronate Hylo-Forte®
    11.08.01 Sodium Hyaluronate Hylo-Tear® Eye drops
    11.99.99.99 Sodium Hyaluronate  
    18 Sodium nitrite 3% Injection  
    02.05.01 Sodium Nitroprusside  Injection (secondary care only)
    09.08.01 Sodium Phenybutyrate Ammonaps®, Pheburane®
    24.01 Sodium Phosphate   0.5mmol (=1.6ml) bd. Prescribe as mmol
    stop at discharge
    01.06.02 Sodium Picosulfate  Elixir 5mg/5ml, capsules (perles) 2.5mg
    01.06.05 Sodium picosulphate with magnesium citrate Picolax®, CitraFleet® Sachet
    02.13 Sodium Tetradecyl Sulphate  Injection (secondary care only)
    18 Sodium thiosulphate 
    04.02.03 Sodium valproate  Tablets 100mg (crushable), 200mg, 500mg, 200mg chrono, 300mg chrono, 500mg chrono
    Bipolar Affective Disorder
  • usual dose range 500mg-1000mg in divided doses
  • max daily dose 2000mg
    		•
    04.08.01 Sodium Valproate Epilim®
    04.08.01 Sodium Valproate Epilim® Intravenous
    04.08.01 Sodium Valproate 
  • Epilim®, Epilim Chrono®, Epilim® injection
    		•
    04.08.01 Sodium Valproate Epilim® Chrono
    10.01.03 Soldium Aurothomalate Myocrisin®
    07.04.02 Solifenacin Vesicare® Tablet 5mg and 10mg
    06.05.01 Somatropin Saizen® Injection
    02.04 Sotalol  Tablet
  • Management of arrythmias.
  • If needed tablets can be crushed and dispersed in water.
    • 02.02.03 Spironolactone  Tablet 25mg, 50mg, 100mg, Oral Suspension 10mg/5ml

  • Potasium sparing diuretic
    		•
    24.01 Spironolactone  1 mg/kg bd initially
    Oral
    Potassium canreonate (Soldactone or Aldactone) 1-1.5mg/kg/dose (usually bd) can be given IV.

    Soldactone dilution: 200mg vial, add 2 ml H20;
    then take 1 ml of this ’Soldactone’ solution and add 9 mls 0.9% NaCl; this solution has 10mg ’Soldactone in 1 ml. Give the appropriate dose as slow bolus over 3 minutes.

    Potassium canreonate also comes as ’Aldactone’. Vial is 200mg in 10 mls. to make up, take 1 ml (=20mg) of solution and dilute to 20mls with 0.9% NaCl. This solution is 1mg/ml. Give the appropriate dose as slow bolus over 3 minutes.
    07.03.03 Spremicidal Contraceptives Gygel®
    03.01.05 Standard range peak flow meter Mini-Wright® Suitable for adults and children
  • 60-800 litres/minute

  • low range also available for adults and children with severely restricted airflow 30-400 litres/minte
    • 05.03.01 Stavudine Zerit®
    02.10.02 Streptokinase  Injection (secondary care only)
    05.01.09 Streptomycin Sulphate 
    01.03.03 Sucralfate Antepsin® Tablet 1 gram, Suspension 1gram/5ml
  • Interacts with enteral feeds and may block NG tubes

  • March 2014 Current supply issues however limited stock available direct from manufacturer - pharmacy to order direct supplies

    • 24.01 Sucrose 66%  Working weight <750g - 0.05ml (31.25mg) max tds
    750g-999g - 0.1ml (62.5mg) max tds
    1000g - 1499g -0.2mls (125mg)
    >1500g - 0.4mls (250mg)
    01.05.01 Sulfasalazine  Tablets 500mg E/C and non E/C
    10.01.03 Sulfasalazine 
    10.01.04 Sulfinpyrazone 
    04.02.01 Sulpiride  Tablet 200mg, 400mg and Liquid 200mg/5ml
    04.07.04.01 Sumatriptan  Tablets 50mg, 100mg
    08.01.05 Sunitinib Sutent®
  • For use in line with NICE TA169, TA178, TA179 & TA449
    		•
    15.01.05 Suxamethonium Chloride 
    24.01 Sytron Sodium Feredetate 0.5 mls tds from 1 month if not on mostly formula feeds
    13.05.02 Tacalcitol Curatoderm®
    02.11 TachoSil Fibrinogen and thrombin
  • Fibrinogen and thrombin dried on to a collagen matrix
  • Restricted to use by urology for use in robotic assisted laparoscopic, laparoscopic and open major urological surgery. Conditions include renal, prostate and bladder cancer

  • Approved at DTC 12/07/2017 for 6 months use to assess whether superior to Surgicel
    		•
    08.02.02 Tacrolimus Adoport®, Prograf®
    13.05.03 Tacrolimus Protopic® Ointment 0.03%, Ointment 0.1%
    08.02.02 Tacrolimus MR Advagraf®
    08.03.04.01 Tamoxifen 
    07.04.01 Tamsulosin  Capsule m/r 400 microgram
    04.07.02 Tapentadol Palexia® Standard release 50mg (tablets)
    Modified release: Palexia SR 50mg, 100mg, 150mg, 200mg, 250mg

    Specialist initiation - for chronic pain in patients either unresponsive or unable to tolerate morphine, fentanyl, oxycodone and buprenorphine (i.e. fifth line strong opioid). Tapentadol can be used 3rd line only if the patient has not responded to morphine and buprenorphine and was showing symptoms of neuropathic pain.

    05.01.07 Teicoplanin Targocid®
    04.01.01 Temazepam  Tablet 10mg and 20mg, Oral solution 10mg/5ml
    Second choice for insomnia
  • Usual dose range: 10-20mg at night
  • Max daily dose 20mg
  • Max single dose 20mg
  • CD storage requirements apply within BTHFT for ALL temazepam products
    • 15.01.04.01 Temazepam 
    08.01.05 Temozolomide Temodal®
    02.10.02 Tenecteplase  Injection (secondary care only)
    05.03.01 Tenofovir and Emtricitabine Truvada®
    05.03.01 Tenofovir Disproxil Viread®
    05.02 Terbinafine 
    13.10.02 Terbinafine   1% cream
    03.01.01.01 Terbutaline  Short-acting beta-agonist
  • Turbohaler (500mcg/dose) and Respules (2.5mg/ml) available
  • Limited use where patient intolerant of salbutamol and in those patients whose condition is exacerbated by an aerosol
    • 06.06.01 Teriparatide Forsteo® injection 250micrograms/ml
    06.05.02 Terlipressin 
    06.04.02 Testosterone and Esters Nebido® Injection
    06.04.02 Testosterone gel  Tostran® Gel 2% (10 mg/metered application),
    06.04.02 Testosterone injection Sustanon 250® Injection
    14.05.02 Tetanus immunoglobulin 
    04.09.03 Tetrabenazine Xenazine® 25
    15.02 Tetracaine (Amethocaine) 
    24.01 Tetracaine 4% AMEPTOP

    Indication: 

    Local anaestetic

    Dose:

    Apply contents of tube (or appropriate proportion) to site

    Administration:

    Site of lumber puncture and cover with occlusive dressing; remove gel and dressing after 30 to 45 minutes for lumber puncture.

    Monitoring:

    Local skin reactions

    Further Info:

    Single use tubes

    Supply:

    Available on NNU as a stock item.

    Stored in Fridge

     
    11.07 Tetracaine Hydrochloride (Amethocaine Hydrochloride) Minims® Eye drops
    06.05.01 Tetracosactide Synacthen® Injection 250micrograms/ml
  • Short Synacthen test (30 min) 250 micrograms as a single dose

    Depot injection 1mg/ml
    		•
    20 TETRAHYDROBIOPTERIN Tablets 10 mg 
    08.02.04 Thalidomide Pharmion®
    03.01.03 Theophylline Nuelin® SA Tablets m/r 250mg
  • Prescribe by brand
  • 175mg tablets not stocked at BTHFT
    		•
    03.01.03 Theophylline Slo-Phyllin® Capsules m/r 60mg, 125mg and 250mg
  • prescribe by brand
  • If necessary Contents of the capsule (enteric-coated granules) may be sprinkled on to a spoonful of soft food (e.g. yoghurt) and swallowed without chewing
    • 03.01.03 Theophylline Uniphyllin® Continus Tablets m/r 200mg, 300mg and 400mg
  • Prescribe by brand
  • May be appropriate to give larger evening or morning dose to achieve optimum therapeutic effect when symptoms most severe in patients whose night or daytime sysmptoms persist despite other therapy, who are not currently recieving theophylline, total daily requirement may be added as single evening or morning dose
    		•
    09.06.02 Thiamine Pabrinex®
  • I/M High Potency injection, for intramuscular use only, ascorbic acid 500 mg, nicotinamide 160 mg, pyridoxine hydrochloride 50 mg, riboflavin 4 mg, thiamine hydrochloride 250 mg/7 mL. (in 2 amps)
    Excipients include benzyl alcohol (avoid in neonates)

  • I/V High Potency injection, for intravenous use only, ascorbic acid 500 mg, anhydrous glucose 1 g, nicotinamide 160 mg, pyridoxine hydrochloride 50 mg, riboflavin 4 mg, thiamine hydrochloride 250 mg/10 mL. (in 2 × 5 mL amps)


  • Wernickes Encephalopathy
    2-3 pairs of ampoules three times a day for 2 to 4 days depending on response

  • Prophylaxis of Wernickes Encephalopathy
    One pair of ampoules twice daily for at least 3 to 5 days
    		•
    09.06.02 Thiamine  Tablets 50mg and 100mg
    Usual dose range: 50 to 100mg TDS
    15.01.01 Thiopental 
    06.04.01.01 Tibolone Livial® Tablet 2.5mg
    02.09 Ticagrelor  Position statement from cardiology to add
    05.01.03 Tigecycline Tygacil®
    13.05.03 Tildrakizumab Ilumetri

    To be prescribed as per NICE guidelines:

    TA575: Tildrakizumab for treating moderate to severe plaque psoriasis
    11.06 Timolol  Eye drops 0.25% and 0.5%
    05.04.02 Tinidazole 
    02.08.01 Tinzaparin Innohep®
    • 10,000 units/ml syringe for subcutaneous injection
    • 20,000 units/ml syringe for subcutaneous injection
    • 20,000 units/ml 2ml vial

     

    • For prophylaxis and treatment of VTE
    08.01.03 Tioguanine Lanvis®
    03.01.02 Tiotropium Spiriva®
  • Inhalation powder 18microgram/dose, capsules for use with Handihaler
  • Respimat device no longer recommended for prescribing
    		•
    02.09 Tirofiban 
    05.01.04 Tobramycin 
    10.01.03 Tocilizumab RoActemra®
    01.05.03 Tofacitinib Xeljanz

    To be used as per NICE guidelines:

    TA547: Tofacitinib for moderately to severely active ulcerative colitis

    Available as oral tablets 
    10.01.03 Tofacitinib Xelijang®
  • Restricted for treatment of rheumatoid arthritis through patient access scheme

  • NICE TA currently in development. Due Jan 2018
    		•
    13.05.03 Tofacitinib Xeljanz

    Oral tablets. 

    As per NICE guidelines for psoriatic arthritis:

    TA543: Tofacitinib for treating active psoriatic arthritis after inadequate response to DMARDs
    24.01 Tolazoline  1 mg/kg IV over 10 mins
    then 0.2-2 mg/kg/hr Stock 25 mg/ml
    Weight x 50 mg tolazoline diluted to 50 mls in 5% dextrose
    1ml/hr = 1mg/kg/hr
    07.04.02 Tolterodine  Tablets 1mg, 2mg
    Capsules modified release 4mg
    13.03 Topical local anaesthetics  Lidocaine 5% ointment
    04.07.04.02 Topiramate 
    04.08.01 Topiramate 
    08.01.05 Topotecan Hycamtin®
    06.01.01.02 Toujeo® Insulin glargine
  • Long acting recombinant human insulin analogue
  • 300 units/ml pre-filled Solostar pen (1.5ml/pen)
  • NOT bioequivalent to insulin glargine 100 units/ml - not directly interchangeable (see SPC)

  • Restricted for initiation by diabetes team
    		•
    04.07.02 Tramadol  Soluble tablet, Capsule, Slow release tablet, Injection
    02.11 Tranexamic Acid  Tablet, Injection
  • Topical solution (unlicensed). In an emergency 500mg/5ml injection can be used topically.

  • If needed tablets can be crushed and dispersed in water.
    		•
    12.03.04 Tranexamic Acid Mouthwash 
    08.01.05 Trastuzumab Herceptin®
    11.06 Travoprost Travatan® Eye drops 40micrograms/ml
    11.06 Travoprost with Timolol DuoTrav® eye drops, travoprost 40micrograms and timolol 5mg/ml
    04.03.01 Trazodone  Capsules and Tablets 50mg, 100mg and 150mg
    Liquid 50mg/5ml
  • Usual dose range 100-300mg daily
  • Max daily dose 600mg
  • Max single dose 300mg
    		•
    08.01.01 Treosulfan 
    06.01.01.02 Tresiba® Insulin Degludec
  • Long acting recombinant human insulin analogue

  • 100units/ml Penfill® cartridges for Novo Nordisk® devices
  • 100units/ml FlexTouch® prefilled pen
  • 200units/ml FlexTouch® prefilled pen
  • Counter shows number of units regardless of strength

  • Restricted to initiation by diabetes team
    		•
    08.01.05 Tretinoin Vesanoid®
    06.03.02 Triamcinolone Kenalog® Intra-articular/intramuscular injection 40mg/ml
    10.01.02.02 Triamcinolone Acetonide Adcortyl® Injection 10mg in 1mL
    10.01.02.02 Triamcinolone Acetonide Kenalog® Injection: 40mg in 1mL
    Vial
    Pre filled syringe
    12.02.01 Triamcinolone Acetonide Nasacort® Nasal spray 55micrograms per spray
    09.08.01 Trientine Dihydrochloride 
    04.02.01 Trifluoperazine  Tablet 1mg, 5mg, Oral solution 1mg/5ml and 5mg/5ml
  • First generation antipsychotic
  • Usual dose range: 2.5mg twice daily initially
  • Max daily dose: 50mg
  • Max single dose: 25mg
    		•
    04.06 Trifluoperazine 
    04.09.02 Trihexyphenidyl 
    05.01.08 Trimethoprim 
    05.01.13 Trimethoprim 
    24.01 Trimethoprim  Treatment mature babies
    4 mg/kg bd oral
    Prophylaxis 2 mg/kg at night
    04.03.01 Trimipramine Surmontil®
    01.03.03 Tripotassium Dicitratobismuthate De-Noltab® Tablets 120mg
  • An addition for second or third line H. pylori eradiction therapy
    		•
    06.07.02 Triptorelin  Decapeptyl®SR, Gonapeptyl Depot®
    08.03.04.02 Triptorelin Gonapeptyl Depot®
    08.03.04.02 Triptorelin- Decapeptyl® SR 
    24.01 Trometamol THAM Try 1.5mmol/kg (5ml) infused over 30mins and then reassess Usual stock is 0.3 Molar =0.3mmol/ml
    Watch for respiratory depression
    20 TROMETAMOL (THAM) 125ML Injection 3.6% (0.3M) 
    11.05 Tropicamide 
  • Mydriacyl® 0.5% and 1% eye drops
  • Minims® Tropicamide 0.5% and 1% single use eye drops
    		•
    07.04.02 Trospium  Tablet 20mg
    Capsule Modified release 60mg
    04.03.04 Tryptophan  Tablets 500mg
    Adjunct for Adult Depression
  • Usual dose range 3-6grams daily in three divided doses
  • Max daily dose 6grams
    		•
    07.03.05 Ulipristal EllaOne® Tablet 30mg, single dose
  • effective if taken within 120 hours (5days) of unprotected intercourse
    		•
    06.04.01.02 Ulipristal acetate 
    03.01.02 Umeclidinium Incruse Ellipta®
    03.01.04 Umeclidinium, vilanterol Anoro Ellipta®
  • Dry powder inhaler
  • Umeclidinium 55 micrograms/vilanterol 22 micrograms
    		•
    13.02.01 Unguentum M®  Cream
    06.05.01 Urofollitropin 
    01.09.01 Ursodeoxycholic acid Ursofalk® Tablet, Capsule, Suspension
    24.01 Ursodeoxycholic Acid   10mg/kg twice daily
    01.05.03 Ustekinumab Stelara®

    To be prescribed as per guidelines:

    TA456: Ustekinumab for moderately to severely active Crohn’s disease after previous treatment

    TA633: Ustekinumab for treating moderately to severely active ulcerative colitis

    In the treatment regimen, the first dose of Stelara is administered intravenously. The first subcutaneous administration of Stelara should take place at week 8 after the intravenous dose. 
    10.01.03 Ustekinumab 
    13.05.03 Ustekinumab Stelara

    As per NICE guidelines:

    TA180: Ustekinumab for the treatment of adults with moderate to severe psoriasis

    TA340: Ustekinumab for treating active psoriatic arthritis

    TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
    05.03.02.01 Valaciclovir Valtrex®
    05.03.02.02 Valganciclovir Valcyte®
    02.05.05.02 Valsartan, sacubitril Entresto® Film coated tablets
    Valsartan 26mg/sacubitril 24mg
    Valsartan 51mg/sacubitril 49mg
    Valsartan 103mg/sacubitril 97mg

  • According to NICE TA388 for treating symptomatic chronic heart failure with reduced ejection fraction
    		•
    05.01.07 Vancomycin 
    24.01 Vancomycin  15 mg/kg/dose bd infused over 1 hour
    Start every 24 hours if <28 weeks.
    Use 12 hourly if postmenstrual age >28/40 and 8 hourly if postmenstrual age >35/40.
    Use with caution if renal impairment 500mg vial dissolved in 4.8 mls water NEEDS FURTHER DILUTION TO
    5 mg/ml by mixing 1ml of this concentrated solution with 19mls 5% dextrose.
    Levels: pre-dose(trough) 10-15 mcg/ml
    04.10.02 Varenicline Champix®
    15.01.05 Vecuronium Bromide 
    01.05.03 Vedolizumab Entyvio®

    Vedolizumab is now available as an IV infusion and SC injection. For more information about dosing, contact the pharmacy or gastroenterology teams.

    To be used as per NICE guidelines:

    TA342: Vedolizumab for treating moderately to severely active ulcerative colitis

    TA352: Vedolizumab for treating moderately to severely active Crohn's disease after prior therapy
    04.03.04 Venlafaxine  Tablets and capsules 37.5mg, 75mg, 150mg.
  • Usual dose range 37.5-75mg twice daily
  • Max daily dose 375mg
    		•
    04.03.04 Venlafaxine Efexor® XL Tablets and Capsules, MODIFIED RELEASE 75mg, 150mg
  • Usual dose range 75-225mg once daily
  • Max daily dose 225mg
  • Max single dose 225mg
    		•
    02.06.02 Verapamil  Tablet, MR tablet, injection (secondary care only)
  • If needed tablets can be crushed and dispersed in water. Do not crush MR formulations.
    		•
    11.08.02 VibeX Rapid® Riboflavin 0.1% 1.5ml pre-filled syringe
  • Restricted to use by opthalmic surgeons for ‘epithelium-off’ photochemical corneal collagen cross-linkage (epithelium-off CXL) to treat progressive keratoconus or keratectasia after laser refractive surgery.
    		•
    04.08.01 Vigabatrin Sabril®
    08.01.04 Vinblastine Sulphate 
    08.01.04 Vinblastine Sulphate Velbe®
    08.01.04 Vincristine Sulphate Oncovin®
    08.01.04 Vincristine Sulphate 
    08.01.04 Vindesine Sulphate Eldisine®
    08.01.04 Vinorelbine 
    08.01.04 Vinorelbine Navelbine®
    09.06.07 Vitamin and mineral supplements Forceval Soluble®
    09.06.07 Vitamin and mineral supplements Ketovite®
    09.06.07 Vitamin and mineral supplements Forceval®
    09.06.02 Vitamin B Tablets, Compound Strong  Tablets
    Usual dose : 2 three times daily
    24.01 Vitamin E Tocopheryl Acetate
  • 50mg once daily O/NG (not a /kg dose)
  • 50mg=75units
    		•
    24.01 Vitamin K Phytomendione
  • 1mg once daily O/NG (not a /kg dose)
  • Base Line clotting required and regularly monitor
    • 09.06.01 Vitamins A and D 
    09.06.01 Vitamins A C and D Healthy Start Children's Vitamin Drops®
    11.08.01 VitA-POS  Eye ointment
    Retinol palmitate 250 units/g, white soft paraffin, light liquid paraffin, liquid paraffin, wool fat

    05.02 Voriconazole Vfend®
    11.03.02 Voriconazole 
    • Intravitreal injection
    • For use by opthalmologists only
    02.08.02 Warfarin  Tablets 0.5mg (white) 1mg (brown), 3mg (blue,) 5mg (pink),
    Suspension 1mg/ml (licensed) - £99 per 150ml
  • If needed tablets can be crushed and dispersed in water.

    • 12.02.02 Xylometazoline Otrivine® spray, for inpatient use, do not use for more than 7 days
    01.07.02 Xyloproct®  Ointment

  • contains lidocaine 5% and hydrocortisone 0.275%
    		•
    03.03.02 Zafirlukast Accolate® Tablet 20mg
    13.02.02 Zinc and Caster Oil Ointment BP  Ointment
    09.05.04 Zinc Sulphate  Effervescent Tablet
  • 45mg elemental zinc
    		•
    06.06.02 Zoledronic Acid  IV infusion 4mg/5ml (Zometa)
  • for reduction of bone damage in advanced malignancies involving bone

    IV infusion 5mg/100ml (50micrograms/ml)
  • Treatment of osteoporosis- Once yearly dose

    		•
    04.01.01 Zolpidem  Tablets 5mg, 10mg
  • Usual dose range: 5-10mg at night
  • Max daily dose 10mg
  • Max single dose 10mg
    		•
    04.08.01 Zonisamide Zonegran®
    04.01.01 Zopiclone  Tablets 3.75mg, 7.5mg
  • Usual dose range: 3.75-7.5mg at night
  • Max daily dose 7.5mg
  • Max single dose 7.5mg
    		•
    04.02.01 Zuclopenthixol Clopixol® Tablet 2mg. 10mg and 25mg
  • First generation antipsychotic
  • Usual dose range: 20-50mg in divided doses
  • Max daily dose: 150mg
  • Max single dose: 50mg
    • 04.02.01 Zuclopenthixol Acetate Clopixol Acuphase® Deep IM injection 200mg/ml snd 500mg/ml
  • Max 600mg weekly
    		•
    04.02.02 Zuclopenthixol Decanoate Clopixol® Depot Injection
    Bradford Teaching Hospitals